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          Lewy bodies

          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·October 8, 2024·4 min read

          Immune Response Linked to Lewy Body Formation

          New research reveals that immune responses play a crucial role in the formation of Lewy bodies, protein aggregates that mark Parkinson's disease and other neurological conditions. Using human stem cells, scientists recreated Lewy bodies in dopaminergic neurons by combining alpha-synuclein protein buildup with immune stimulation.
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          This shows the outline of a head
          FeaturedGeneticsNeurosciencePsychology
          ·January 10, 2022·5 min read

          Neurons Derived From Stem Cells Predict Psychosis and Cognitive Deficits in Individuals With Schizophrenia

          Clinical symptoms of schizophrenia, such as psychosis and cognitive deficits, can be predicted from the activity of neurons derived from a patient's stem cells.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·September 8, 2021·2 min read

          New Information on the Early Stages of Dementia With Lewy Bodies

          New findings reinforce the idea that dementia with Lewy bodies can be pathologically classified as two different and distinct disease types.
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          This cartoon shows the outline of people
          FeaturedGeneticsNeurologyNeuroscience
          ·February 16, 2021·5 min read

          Genetic Study of Lewy Body Dementia Supports Ties to Alzheimer’s and Parkinson’s Diseases

          Study identified five genes, including two novel genes, associated with Lewy Body dementia. Researchers also found the genetic profiles of patients with LBD showed higher chances of also suffering from Alzheimer's and Parkinson's disease than other age-matched control subjects.
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          This is a computerized representation of a neuron
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·February 10, 2021·4 min read

          Function Identified of ‘Mystery Protein’ That Kills Brain Cells of People With Parkinson’s

          Study sheds new light on the damage alpha-synuclein does to neurons in Parkison's disease patients.
          Read More
          This shows a brain slice of a patient with PD
          FeaturedGeneticsNeurologyNeuroscience
          ·January 5, 2021·4 min read

          Artificial Enzyme May Be First Step Toward Treatment for Parkinson’s Disease

          Researchers have created an artificial enzyme that stops alpha-synuclein from spreading. The findings could have positive implications for the treatment of Parkinson's disease.
          Read More
          This shows the misfolded proteins
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·August 23, 2020·4 min read

          Unique Protein Structures Could Hold the Key to Parkinson’s Disease

          Researchers have discovered a series of misfolded alpha-synuclein protein structures never previously observed. The alpha-synuclein fibers were larger than previously reported and adopted a striking variety of shapes. The work lays the foundation for a detailed analysis of misfolded alpha-synuclein structures and could provide a better understanding of the neurobiology of Parkinson's disease.
          Read More
          This shows neurons
          FeaturedNeurologyNeuroscience
          ·March 13, 2020·5 min read

          ‘Natural killer’ cells could halt Parkinson’s progression

          Natural killer cells may play a critical role in regulating and restraining neuroinflammation and protein clumping associated with Parkinson's disease.
          Read More
          This shows lewy bodies
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·July 29, 2019·4 min read

          Discovery could lead to new treatments for Parkinson’s, other brain diseases

          New model could inform the development of new treatments for Lewy body diseases by targeting alpha-synuclein DNA repair mechanisms.
          Read More
          This shows marmoset monkeys
          FeaturedNeurologyNeuroscience
          ·May 10, 2019·4 min read

          Inflamed monkey guts produce Parkinson’s-related proteins

          Inflammation of the colon is associated with alterations in alpha-synuclein expression and phosphorylation in the myenteric plexus of common marmoset monkeys. The findings support the growing body of evidence that inflammation may play a role in the development of Parkinson's disease.
          Read More
          alzheimers brain
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·February 19, 2019·4 min read

          Study Finds Ethnoracial Differences in Alzheimer’s

          A new study reveals Hispanic Americans diagnosed with Alzheimer's disease tend to survive significantly longer with the condition than people from other ethnoracial groups.
          Read More
          graphic abstract
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·January 10, 2019·4 min read

          Defective Glial Cells Can Push Neurons Toward Parkinson’s Disease

          A new study reveals a defective version of astrocytes may be linked to the build up of alpha synuclein and could spur Parkinson's disease. The findings show the important role glial cells play in Parkinson's and offers insights into new targets for therapies to fight the neurodegenerative disease.
          Read More
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          This shows a head and a brain.

          Why Memories Change: How the Brain Rewrites the Past

          This shows a brain and a cigarette.

          Astrocytes Found to Drive Key Brain Changes in Nicotine Addiction

          This shows two people hugging.

          Warmth and Hugging Strengthen the Feeling of Being You

          This shows a person drinking from a plastic water bottle and a brain.

          Microplastics Accelerate Alzheimer’s and Parkinson’s Damage

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