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Lewy bodies

·March 13, 2020·5 min read

‘Natural killer’ cells could halt Parkinson’s progression

Natural killer cells may play a critical role in regulating and restraining neuroinflammation and protein clumping associated with Parkinson's disease.

This image shows positive α-Synuclein staining of a Lewy body in a patient with Parkinson's disease.

Featured Neurology

·September 29, 2014·2 min read

A “Frenemy” in Parkinson’s Disease Takes to Crowdsourcing

A protein associated with Parkinson's disease regulates neurotransmission by self association, a new study reports.

Featured Neurology

·February 1, 2016·3 min read

A Better Model for Parkinson’s Disease

Researchers improve both animal and cell models for Parkinson's disease, a new study reports.

Image shows positive α-Synuclein staining of a Lewy body from a patient who had Parkinson's disease.

Featured Genetics Neurology

·June 8, 2016·5 min read

A Key to Parkinson’s Neurodegeneration Identified

A new study reports the interaction between a mitochondrial protein called TOM20 and alpha-synuclein leads to neurodegeneration in Parkinson's disease.

Image shows nerve fiber in the submandibular gland.

Featured Neurology

·April 12, 2016·4 min read

A Tissue Biomarker for Dementia With Lewy Bodies and Parkinson’s Disease

Biopsy of submandibular gland may reveal signature alpha-synuclein associated with Parkinson's disease and dementia with Lewy bodies.

Featured Neurology

·September 30, 2016·3 min read

Abnormal Brain Protein May Contribute to Development of Alzheimer’s

A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.

This image is a labeled diagram of an alzheimer's brain slice.

Featured Neurology

·July 15, 2015·3 min read

African-American and European-American Brains Affected Differently by Alzheimer’s

Researchers discover different pathologies affect the brains of European and African American alzheimer's patients.

This image shows plastinated brains with alzheimers.

Featured Neurology

·February 27, 2014·3 min read

After Death, Twin Brains Show Similar Patterns of Neuropathologic Changes

Researchers compared the brains of twins where one, or both, died with Alzheimer's disease. They discovered many of the twins not only had similar progressions of the disease before death, but also similar combinations of pathologies.

Image shows a Parkinson's disease brain sample.

Featured Neurology

·July 3, 2017·4 min read

Alzheimer’s and Parkinson’s Spurred By Same Enzyme

Researchers have implicated an enzyme that appears to make both Tau and alpha synculein more toxic in Alzheimer's and Parkinson's disease. Inhibiting this enzyme has already proved helpful in treating animal models of Alzheimer's disease. The researchers report they are moving on to testing drugs that inhibit AEP in animal models of Parkinson's disease.

Featured Neurology Open Neuroscience Articles

·October 31, 2018·5 min read

Appendix Removal May Lower Parkinson’s Risk

Researchers report those who have had appendectomies have a reduced risk of developing Parkinson's disease. A new study reveals the appendix acts as a reservoir for proteins associated with the neurodegenerative disease.

This shows a brain slice of a patient with PD

Featured Genetics Neurology Neuroscience

·January 5, 2021·4 min read

Artificial Enzyme May Be First Step Toward Treatment for Parkinson’s Disease

Researchers have created an artificial enzyme that stops alpha-synuclein from spreading. The findings could have positive implications for the treatment of Parkinson's disease.