A new study aims to generate a model of how the brain and body fat communication system controls the production and release of leptin. The study aims to discover how metabolism is regulated under different environmental challenges.
Interleukin-6 interacts with leptin in the lateral parabrachial nucleus to reduce food intake. Reducing IL-6 in the IPBL increases weight gain and could help explain why some are more prone to overeating and obesity.
A new neuroimaging study found those who achieved greater success at losing weight showed increased activation in regions of the lateral prefrontal cortex, an area of the brain associated with self control.