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L-dopa

Brain scans with the vmPFC and VS highlighted.

Featured Open Neuroscience Articles Psychology

·November 20, 2015·4 min read

Reward Circuits Weakened by Inflammation in Depression

Researchers find high level of inflammation markers in the blood of people with depression. The research indicates persistent inflammation affects brain areas associated with the more stubborn symptoms of depression.

Featured Neurology Open Neuroscience Articles

·May 3, 2016·3 min read

Transplanted Nerve Cells Survive 25 Years in Parkinson’s Patient

Researchers report transplanted nerve cells can survive for a number of years and restore dopamine production in Parkinson's patients.

Featured Neurology Open Neuroscience Articles

·May 5, 2016·4 min read

Improving Cell Transplants for Parkinson’s Patients

Researchers used a new technique to discover what happens when Parkinson's patients receive cell transplants.

This shows two head outlines with drawings of brains in them

Featured Genetics Neurology Neuroscience

·July 6, 2019·4 min read

To cure brain diseases, neuroscientists must collaborate: That’s why I’m giving my data away

Open sharing of scientific data and standard methods will allow researchers to collaborate on projects and accelerate understanding of neurodegenerative diseases.

This is the striatonigral pathway in the basal ganglia.

Featured Neurology

·September 10, 2015·4 min read

Why Long Term Use of L-DOPA for Parkinson’s Disease Leads to Dyskinesia

A new study reports Parkinson's related dyskinesia occurs when striatonigral neurons become less responsive to GABA.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 13, 2019·6 min read

Gut Bacteria Interferes with Metabolism of Parkinson’s Drug

Study provides first concrete examples of how the microbiome can interfere with a drug's intended path throughout the body.

Featured Neuroscience Open Neuroscience Articles

·July 28, 2015·4 min read

Sleep Deprivation Reduces Aggression and Mating Behavior in Fruit Flies

A new study reports a lack of sleep can reduce aggression and affect reproductive fitness in fruit flies.

Diagram shows the location of the nucleus accumbens in the brain.

Featured Neurology Pain

·December 21, 2015·4 min read

New Drug Therapy Could End Chronic Pain

Drug combination targets brain circuits in the nucleus accumbens and completely eliminate chronic pain behavior.

Image shows a person at a cross roads with signs saying risk and safe.

Featured Neuroscience

·July 27, 2016·5 min read

Neural Circuits Involved in Making Risky Decisions Identified

Researchers have uncovered what goes on in our brains when we are faced with the decision to take a risk or play it safe.

This shows a model of a head and a brain

Featured Genetics Neurology Neuroscience

·March 1, 2021·6 min read

Individualized Brain Cell Grafts Reverse Parkinson’s Symptoms

Grafting neurons derived from a monkey's own stem cells reversed the debilitating and mental health symptoms associated with Parkinson's disease. The treatment shows promise for alleviating the symptoms of Parkinson's in humans.

Featured Genetics Neurology Neuroscience

·May 11, 2022·7 min read

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson's associated destruction of dopaminergic cells.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 24, 2021·3 min read

Sonic Hedgehog Protein Pathway Stimulation Could Help Parkinson’s Patients

Drugs that increase signaling of Sonic Hedgehog (Shh) can help suppress the involuntary movements associated with dopamine replacement therapy for those with Parkinson's disease.

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L-dopa

Reward Circuits Weakened by Inflammation in Depression

Transplanted Nerve Cells Survive 25 Years in Parkinson’s Patient

Improving Cell Transplants for Parkinson’s Patients

Why Long Term Use of L-DOPA for Parkinson’s Disease Leads to Dyskinesia

Gut Bacteria Interferes with Metabolism of Parkinson’s Drug

Sleep Deprivation Reduces Aggression and Mating Behavior in Fruit Flies

New Drug Therapy Could End Chronic Pain

Neural Circuits Involved in Making Risky Decisions Identified

Individualized Brain Cell Grafts Reverse Parkinson’s Symptoms

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Sonic Hedgehog Protein Pathway Stimulation Could Help Parkinson’s Patients

New Insights Into Synaptic Pruning During Brain Development

Childhood IQ and Wealth: Uncovering Diverse Financial Paths in Adulthood

Stressed Brains Amplify Comfort Food Cravings

Ozempic Shows Potential as Treatment for Alcohol Dependence

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