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Klotho

·May 8, 2025·4 min read

Boosting Klotho Protein Slows Aging and Enhances Health

Increasing levels of the Klotho protein can slow aging and improve health across multiple systems. Scientists showed that mice treated to produce more secreted Klotho (s-KL) had better muscle strength, bone density, cognitive function, and even lived 15–20% longer.

This shows a numerous different graphs from the study

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·November 2, 2021·2 min read

Mini-Brain Models Used in Hunt for Alzheimer’s Treatment

Brain organoids can be used to study molecular mechanisms that drive brain aging and neurodegenerative disorders. The mini-brains allow for the testing of molecules that could become potential therapeutic treatment options for neurodegenerative diseases.

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·June 10, 2021·5 min read

Memory Biomarkers Confirm Aerobic Exercise Helps Cognitive Function in Older Adults

Researchers have identified three biomarkers in blood samples that confirm the link between exercise and improved cognitive function in older adults.

this shows the outline of a woman and an hour glass

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·May 30, 2021·3 min read

Intermittent Fasting Improves Long Term Memory

Mouse study reveals intermittent fasting improves long-term memory retention and promotes hippocampal neurogenesis. The findings could help to slow cognitive decline in older adults.

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·April 13, 2020·7 min read

Gene variant staves off Alzheimer’s in some people

Carriers of one copy of the longevity associated klotho gene reduces Alzheimer's risks by 30% for those with genetic risk factors for the neurodegenerative disease.

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·November 12, 2018·3 min read

New Insights Into the Aging Brain

A new study reports klotho, a protein associated with longevity, acts as a gatekeeper that helps shield the brain from the peripheral immune system.

Featured Genetics

·January 30, 2018·2 min read

Could a Protein Called Klotho Block Dementia and Aging?

Genetically increasing klotho helps boost cognitive function in mice models of Alzheimer's disease, researchers report.

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·August 10, 2017·6 min read

Hormone Shows Promise as Cognition Enhancer

Researchers report klotho, a life extending protein, improved working memory, spatial memory and learning in mice. The researchers also noted a single injection of klotho was sufficient to improve cognitive ability and the effects were long lasting.

This image showsa women who looks depressed.

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·June 16, 2015·4 min read

Depressed and Stressed Women Have Lower Levels of Longevity Hormone

A new study reports women with symptoms of clinical depression have lower levels of klotho in their blood.

This image shows the Clotho from greek mythology. she is standing on a strand of DNA.

Featured Genetics

·May 8, 2014·4 min read

Better Cognition Seen with Gene Variant Carried by 1 in 5 People

Researchers discover a gene already associated with longevity also improves memory and learning. The findings could help develop new treatments for cognitive decline.

The image shows an oligodendrocyte transfected with GFP (Green Fluorescent Protein).

Featured Neuroscience

·January 30, 2013·2 min read

New Drug Target Identified for Multiple Sclerosis and Alzheimer’s Disease

Researchers report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD).