Increasing SIRT3 levels with a ketone rich diet may help protect GABAergic interneurons and delay the onset of Alzheimer's disease.
Rats fed on a high-fat diet were more mentally exhausted following a novel object recognition test than those fed a healthier diet. Findings suggest high-fat diets not only contribute to obesity, but they can also have an impact on mental fatigue and cognitive abilities.
In the short term, a ketogenic diet can help improve health as well as assist in weight loss. However, the negative effects of the keto diet start to appear after one week. Mice who were fed a ketogenic-style diet for more than seven days consumed more fat than they could burn, and had an increased risk of developing diabetes and obesity.
A small scale pilot study reveals adults with mild cognitive impairment may have improved brain function and memory when they switch to a high-fat, low-carb diet.
A new study explains how, at the molecular level, exercise benefits he mammalian brain.