Study identifies a potential drug target in the skin for itching.
Study could help explain how pain often follows a chemical induced itch.
Researchers have discovered a dedicated neural pathway that transmits the itchy feeling triggered by light touch.
A new study reports on how sensory neurons work together to transmit itch signals from the skin, via the spinal cord and to the brain.
According to researchers, socially contagious itching may be hard wired in the brain.
Blocking the NPR1 receptor on the spinal cords of mice and humans may help reduce chronic itching.
Researchers identified a set of neurons in the spinal cord that transmits a light-touch signal from the skin to the brain. NPY-Y1 signaling regulates the transmission of innocuous tactile information by establishing thresholds for touch discrimination and mechanical itch reflexes. The findings shed new light on the neurobiological basis of chronic itching.
Periostin can directly activate neurons associated with itching. Blocking periostin receptors reduced itch response in mouse models of chronic allergic itching.
Stroking the skin can be as effective at relieving an itch as scratching, a new study reports. Rubbing an itch activates touch receptors and recruits anti-itch neurons in the spinal cord.
