A low dose of the sedative clonazepam alleviated autistic-like behavior in mice with a mutation that causes Dravet syndrome in humans.
Researchers discovered a new group of nerve cells that regulate processes of learning and memory. These cells act as gatekeepers and carry a receptor for nicotine, which can help explain our ability to remember and sort information. The newly discovered gatekeeper nerve cells, also called OLM-alpha2 cells, provide an explanation to how the flow of information is controlled in the hippocampus.
A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.
New research discovers an early step in how the brain's inhibitory cells get excited. Erbin, a protein critical to brain development, is also crucial for the excitement of inhibitory cells.
VIP interneurons specialize in inhibiting other inhibitory neurons in multiple regions of the cerebral cortex under specific behavioral conditions, a new study shows.
Researchers discover how parvalbumin-expressing interneurons, which usually limits stem cell activity, can also encourage the survival of the stem cells' progeny.
Researchers develop a novel system to image worm brain activity. The new technology makes it possible for researchers to study the neural circuitry and genetics associated with animal behavior.
Transplanted neurons derived from stem cells shown to be effective in treating epilepsy in mice, a new study reports.
A new paper hypothesizes that a particular type of interneuron may influence responses in a context dependent manner.
Researchers observe and measure synaptic transmission in a live animal using optogenetics.