interleukin 6

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interleukin 6

Featured Neuroscience Open Neuroscience Articles

·May 20, 2020

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

SARS-CoV-2, the virus responsible for COVID-19, enters human cells by attaching to ACE2 and utilizing TMPRSS2. Drugs that block ACE2 or inhibit the enzyme could help treat the coronavirus, but only during early infection. As the infection progresses, SARS-CoV-2 becomes engulfed in human cells, reducing the number of ACE2 receptors on a cell and leading to an increase of angiotensin II in the blood. Angiotensin II triggers an inflammatory pathway, providing a positive feedback cycle, named IL-6 amplifier, resulting in excessive immune activation and the cytokine storm associated with severe COVID-19. Read More

This shows a weighing scale, a tape measure and an apple

Featured Neuroscience Open Neuroscience Articles

·May 2, 2019

New brain mechanisms regulating body weight identified: Rodent study

Interleukin-6 interacts with leptin in the lateral parabrachial nucleus to reduce food intake. Reducing IL-6 in the IPBL increases weight gain and could help explain why some are more prone to overeating and obesity. Read More

Featured Genetics Neurology pain

·April 8, 2019

Migraine-linked protein exhibits sex-specific pain effects

CGRP, a protein associated with migraine pain, appears to act differently between sexes. Researchers say a female-specific mechanism of downstream CGRP receptor activation is likely to contribute to the higher prevalence of migraine in women. Read More

Featured Neuroscience

·December 27, 2018

How Exercise Reduces Belly Fat in Humans

According to researchers, interleukin 6 plays a critical role in how exercise helps to reduce body fat. Read More

artificial intelligence deep learning Featured Neuroscience

·April 9, 2018

Study Confirms Inflammation During Pregnancy is Linked to Baby’s Brain Development

A new study confirms previous findings that link inflammation during pregnancy to altered brain development in children. Researchers have created a machine learning algorithm that can predict the long term neurodevelopmental impact of MIA. Read More

Autism Featured Genetics Neuroscience

·November 10, 2017

iPSCs Show Astrocyte-Neuron Impact on Brain Pathology in Autism

A new study in Biological Psychiatry reports researchers discovered astrocytes may contribute to the cause of ASD. The findings could help to develop new treatments for autism spectrum disorders. Read More

Image shows a girl holding up an autism sign.

Autism Featured Neuroscience

·October 18, 2017

Inflamed Support Cells Appear to Contribute to Some Kinds of Autism

A new study demonstrates astrocytes play a role in certain subtypes of autism spectrum disorder. Read More

Flow chart extablishes the link between stress and diabetes.

Featured Neurology

·June 6, 2016

Researchers Detail Link Between Stress and Diabetes

Researchers report they have established a link between emotional stress and diabetes. Read More

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Featured Open Neuroscience Articles Psychology

·February 25, 2016

Immunotherapy May Improve Cognition in People With Schizophrenia

A small study supports the mounting evidence that targeted immunotherapy can help improve cognitive ability in people with schizophrenia. Read More

Image shows crystal structure of IL-6 as published in the Protein Data Bank.

Featured Psychology

·January 26, 2016

Monoclonal Antibody Shows Promise for Reducing Memory and Learning Problems in Schizophrenia

Researchers report a monoclonal antibody that shows promise in the fight against cancer also appears to help reduce learning and memory problems associated with schizophrenia. Read More

Featured Genetics Open Neuroscience Articles

·January 11, 2016

New Evidence For Immune System Plasticity

A new study reports researchers have developed a method to influence long term memory formation in the immune system. Read More

Autism

·February 14, 2012

Undergrad’s Work Details Protein’s Role in Neurological Disorders

Student and prof. study suspected link to hyper-excitability factors in epilepsy, autism and more. A UT Dallas undergraduate’s research is... Read More