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          Institute For Basic Science

          This shows a brain and neurons representing pain.
          FeaturedNeurologyNeurosciencePain
          ·March 5, 2025·4 min read

          Brain Distinguishes Pain and Itch Using Separate Neural Circuits

          A new study reveals that pain and itch are processed by distinct neural circuits in the anterior cingulate cortex (ACC). Researchers identified two types of neurons—one responding to both stimuli and another selectively activated by either pain or itch.
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          This shows a brain.
          AutismFeaturedGeneticsNeuroscience
          ·December 27, 2024·5 min read

          Lithium Restores Brain Function and Behavior in Autism

          Lithium, a drug widely used for bipolar disorder, may also treat autism spectrum disorder (ASD), according to new research. The study found that lithium restored brain function and reduced behavioral symptoms in mice with Dyrk1a gene mutations, a known ASD risk factor.
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          This shows a woman with an orange glow around her head.
          ElectrophysiologyFeaturedNeurologyNeurosciencePain
          ·September 23, 2024·5 min read

          How the Brain Integrates Pain Expectations and Reality

          New research reveals how the brain combines pain expectations with actual pain intensity, offering insights into the brain's pain integration process. Using fMRI, scientists found that while all brain networks store pain information, only higher-level networks integrate pain expectations and stimuli into a cohesive experience.
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          This shows a head.
          FeaturedNeuroscience
          ·June 11, 2024·4 min read

          Brain’s Dual Response to Pain and Pleasure Unveiled

          Researchers discovered that the brain processes pain and pleasure through overlapping regions. By analyzing sustained pain from capsaicin and pleasure from chocolate, they identified distinct brain activity patterns linked to both experiences. These findings enhance our understanding of the brain’s mechanisms for emotional responses. The study could have implications for treating chronic pain and depression.
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          This shows a young boy.
          AutismFeaturedGeneticsNeuroscience
          ·May 9, 2024·4 min read

          Key Brain Region Implicated in Autism Sensory Issues

          Researchers identified the anterior cingulate cortex (ACC) as a crucial area linked to sensory hypersensitivity in autism spectrum disorders (ASD). This sensory hypersensitivity, affecting about 90% of individuals with autism, leads to abnormal responses to stimuli like sound and light, complicating daily activities and social interactions.
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          This shows a woman's head.
          FeaturedNeurosciencePsychology
          ·April 11, 2024·5 min read

          AI Can Now Read Your Daydreams

          Researchers developed methods to predict emotions in spontaneous thoughts using fMRI and machine learning. They crafted personalized narratives that participants read while their brain activity was monitored, aiming to decode the emotional dimensions of thoughts.
          Read More
          This shows a brain scan.
          FeaturedNeurologyNeuroscience
          ·February 23, 2024·4 min read

          Ultrasound Brain Stimulation: A Significant Leap in Neurotherapy

          Researchers introduced a groundbreaking non-invasive brain stimulation technique called Patterned Low-Intensity Low-Frequency Ultrasound (LILFUS). This innovative method can precisely target and modulate specific brain regions, offering a promising alternative to traditional magnetic, electrical, and surgical brain stimulation methods with fewer risks.
          Read More
          This shows a head.
          FeaturedNeuroscience
          ·January 26, 2024·5 min read

          Nasal Lymphatic Network Crucial for Brain CSF Drainage

          Researchers discovered a crucial network of lymphatic vessels at the back of the nose, which significantly contributes to draining cerebrospinal fluid (CSF) from the brain. This study reveals a previously unknown CSF outflow route, offering insights into neurodegenerative conditions.
          Read More
          This shows a brain model.
          FeaturedNeuroscience
          ·December 18, 2023·3 min read

          AI Memory Mirrors Human Brain

          Researchers unveiled a significant similarity between AI memory processing and human hippocampal functions. This discovery, bridging AI and neuroscience, highlights a parallel in memory consolidation - a process crucial in transforming short-term to long-term memories - in both AI models and the human brain.
          Read More
          This shows a brain on a plate.
          FeaturedNeuroscience
          ·August 31, 2023·5 min read

          Brain’s Weight Switch Found: Eat What You Want, Lose Weight With New Treatment

          A revolutionary discovery reveals that astrocytes, star-shaped cells in the brain, play a key role in regulating fat metabolism and obesity. These cells act on a cluster of neurons, known as the GABRA5 cluster, effectively acting as a "switch" for weight regulation.
          Read More
          This shows a woman.
          FeaturedNeurosciencePsychology
          ·June 29, 2023·4 min read

          Decoding Repetitive Negative Thoughts: Machine Learning Predicts Rumination

          A team of researchers have developed a predictive model to recognize patterns of persistent negative thinking, or rumination, using machine learning. Researchers hypothesized that the variance of dynamic connectivity between certain brain regions, such as the dorsal medial prefrontal cortex (dmPFC), could be associated with rumination.
          Read More
          This shows neurons.
          FeaturedNeuroscience
          ·June 1, 2023·6 min read

          Hippocampal Neurons Hold Key to Social Recognition

          Using a new experimental paradigm in mice, the study showed that the CA1 region plays an essential role in individual recognition.
          Read More
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          This shows a middle aged woman.

          Mapping the Brain’s Resting Grid Through Menopause

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          Parental Infertility Biology, Not IVF, Linked to Child Autism Traits

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          Glucosamine Supplement Linked to Accelerated Alzheimer’s Progression

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          Silencing One Brain Gene May Reverse Autism Deficits

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