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          Institute For Basic Science

          This shows a brain and face.
          FeaturedNeuroscience
          ·June 5, 2025·5 min read

          Facial Stimulation Clears Brain Waste and Boosts Aging Minds

          Researchers have discovered a safe, non-invasive way to enhance the brain’s waste clearance system by mechanically stimulating lymphatic vessels just beneath the facial skin. This gentle technique significantly improves cerebrospinal fluid (CSF) drainage—a critical function that declines with age and contributes to cognitive disorders like Alzheimer’s.
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          This shows genes and neurons.
          FeaturedGeneticsNeuroscience
          ·May 23, 2025·5 min read

          Tiny Genetic Code Disruption Alters Brain Wiring and Behavior

          A small genetic sequence called mini-exon B plays a surprisingly crucial role in how neurons form synaptic connections, according to new research. Scientists found that deleting this four–amino acid segment from a synapse-building protein, PTPδ, disrupted neural activity and led to anxiety-like behaviors in mice.
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          This shows the outline of a person.
          FeaturedNeuroscience
          ·April 1, 2025·5 min read

          Brain Circuit for Vicarious Fear Reveals How We Feel Others’ Pain

          Scientists have uncovered a dedicated brain circuit that distinguishes between direct fear and fear learned by observing others—known as vicarious fear. The study shows that the right side of the brainstem’s locus coeruleus (LC) activates a specific pathway to the anterior cingulate cortex (ACC) during vicarious fear, while the left side processes direct fear.
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          This shows two brains.
          FeaturedNeuroscience
          ·March 11, 2025·4 min read

          Brain Circuit Discovery Reveals How Empathy Shapes Our Behavior

          Researchers have discovered how specific brain circuits process empathy, showing that witnessing others in pain activates the same neural pathways as experiencing pain directly. Using advanced imaging techniques, the study pinpointed neurons in the anterior cingulate cortex (ACC) that respond both to personal distress and observed distress in others. The scientists further demonstrated that signals from the ACC to the brain’s periaqueductal gray (PAG) region are crucial for transforming empathy into behavioral responses, like freezing or avoidance.
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          This shows a brain and neurons representing pain.
          FeaturedNeurologyNeurosciencePain
          ·March 5, 2025·4 min read

          Brain Distinguishes Pain and Itch Using Separate Neural Circuits

          A new study reveals that pain and itch are processed by distinct neural circuits in the anterior cingulate cortex (ACC). Researchers identified two types of neurons—one responding to both stimuli and another selectively activated by either pain or itch.
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          This shows a brain.
          AutismFeaturedGeneticsNeuroscience
          ·December 27, 2024·5 min read

          Lithium Restores Brain Function and Behavior in Autism

          Lithium, a drug widely used for bipolar disorder, may also treat autism spectrum disorder (ASD), according to new research. The study found that lithium restored brain function and reduced behavioral symptoms in mice with Dyrk1a gene mutations, a known ASD risk factor.
          Read More
          This shows a woman with an orange glow around her head.
          ElectrophysiologyFeaturedNeurologyNeurosciencePain
          ·September 23, 2024·5 min read

          How the Brain Integrates Pain Expectations and Reality

          New research reveals how the brain combines pain expectations with actual pain intensity, offering insights into the brain's pain integration process. Using fMRI, scientists found that while all brain networks store pain information, only higher-level networks integrate pain expectations and stimuli into a cohesive experience.
          Read More
          This shows a head.
          FeaturedNeuroscience
          ·June 11, 2024·4 min read

          Brain’s Dual Response to Pain and Pleasure Unveiled

          Researchers discovered that the brain processes pain and pleasure through overlapping regions. By analyzing sustained pain from capsaicin and pleasure from chocolate, they identified distinct brain activity patterns linked to both experiences. These findings enhance our understanding of the brain’s mechanisms for emotional responses. The study could have implications for treating chronic pain and depression.
          Read More
          This shows a young boy.
          AutismFeaturedGeneticsNeuroscience
          ·May 9, 2024·4 min read

          Key Brain Region Implicated in Autism Sensory Issues

          Researchers identified the anterior cingulate cortex (ACC) as a crucial area linked to sensory hypersensitivity in autism spectrum disorders (ASD). This sensory hypersensitivity, affecting about 90% of individuals with autism, leads to abnormal responses to stimuli like sound and light, complicating daily activities and social interactions.
          Read More
          This shows a woman's head.
          FeaturedNeurosciencePsychology
          ·April 11, 2024·5 min read

          AI Can Now Read Your Daydreams

          Researchers developed methods to predict emotions in spontaneous thoughts using fMRI and machine learning. They crafted personalized narratives that participants read while their brain activity was monitored, aiming to decode the emotional dimensions of thoughts.
          Read More
          This shows a brain scan.
          FeaturedNeurologyNeuroscience
          ·February 23, 2024·4 min read

          Ultrasound Brain Stimulation: A Significant Leap in Neurotherapy

          Researchers introduced a groundbreaking non-invasive brain stimulation technique called Patterned Low-Intensity Low-Frequency Ultrasound (LILFUS). This innovative method can precisely target and modulate specific brain regions, offering a promising alternative to traditional magnetic, electrical, and surgical brain stimulation methods with fewer risks.
          Read More
          This shows a head.
          FeaturedNeuroscience
          ·January 26, 2024·5 min read

          Nasal Lymphatic Network Crucial for Brain CSF Drainage

          Researchers discovered a crucial network of lymphatic vessels at the back of the nose, which significantly contributes to draining cerebrospinal fluid (CSF) from the brain. This study reveals a previously unknown CSF outflow route, offering insights into neurodegenerative conditions.
          Read More
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          This shows two people and a brain.

          Smarter Minds Predict Better: IQ Linked to Sharper Life Forecasting

          This shows the outline of a head and a brain.

          Brain Structure Differences Linked to Antisocial Traits in Psychopathy

          This shows a person sleeping and a brain.

          Short Naps Linked to “Aha” Moments and Creative Insight

          This shows a robosurgeon and a heart.

          Robotic Heart Transplant Marks Surgical Breakthrough

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