inflammatory bowel disease

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inflammatory bowel disease

·May 17, 2019·4 min read

Adult-onset inflammatory bowel disease linked to higher mortality

Diagnosis of inflammatory bowel diseases like Crohn's disease and ulcerative colitis during adulthood has been linked to a 50% higher mortality rate and shorter life expectancy in those over 50. The increased risk of death remained after the introduction of therapies aimed at treating the conditions but decreased over time. Read More

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·April 24, 2018·5 min read

Common Anti-Inflammatory Therapy May Reduce Parkinson’s Risk

Researchers reveal patients with inflammatory bowel disease are 28% more likely to develop Parkinson's disease. However, an anti-inflammatory treatment used to help those with IBD can significantly decrease the risk of developing the neurodegenerative disease. Read More

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·October 23, 2017·4 min read

Connection Between Microbiome and Autoimmune Disorders

A new mechanism in the gut microbiome has implications for autoimmune disorders, a new study reveals. Read More

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·January 3, 2020·6 min read

Fat-dissolving bile acids may help regulate gut immunity and inflammation

Two studies reveal the role bile acids play in immunity and inflammation. Read More

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·November 5, 2017·5 min read

Gut Bacteria Linked to Age Related Conditions

Researchers transplanted gut bacteria from older mice into young mice and noted age related chronic inflammation following the procedure. The process, dubbed inflammaging, is linked to conditions associated with older age such as stoke and dementia. Read More

Featured Neuroscience

·October 24, 2019·5 min read

Gut instincts: Researchers discover first clues on how gut health influences brain health

Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems. Read More

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·February 11, 2020·6 min read

Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

A new 3D human gut organoid reveals the molecular system that keeps the intestinal linings sealed and how dysfunction can occur. Findings reveal the diabetes drug metformin can help strengthen the intestinal lining. Read More

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·August 19, 2019·6 min read

Increased risk of psychiatric disorders in children with inflammatory bowel disease

Children with inflammatory bowel disease (IBD) are at increased risk of being diagnosed with a mental health problem. The risk of being diagnosed with a psychiatric condition is 1.6 times higher for those with IBD than the general population. IBD is associated with an increased risk of eating disorders, anxiety, depression, personality disorders, and ASD diagnosis. Researchers report there is also an increased risk of suicidal thoughts when the child reaches adulthood. The risk of being diagnosed with a psychiatric disorder was highest during the first year of IBD diagnosis, especially in children diagnosed with the condition before the age of 6. Read More

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·November 14, 2019·5 min read

Inflammatory bowel disease appears to impact risk of Parkinson’s disease

Study provides new insights into how the immune system and inflammation play a role in the development and progression of Parkinson's disease. Read More

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·July 3, 2019·2 min read

Study provides insights into depression in people with inflammatory bowel disease

A link between disease activity in those with inflammatory bowel disease and less positive biases in emotional regulation could explain a higher risk of depression in those with IBD. Read More

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·November 14, 2019·4 min read

Sugar binges increase risk of inflammatory bowel disease

Short term increases in sugar consumption raise the susceptibility to colitis and worsen symptoms of inflammatory bowel disease in mouse models. Read More