Biologically active polysaccharides from red algae known as carrageenan appear to suppress the activity of peritoneal phagocytes in mice, generating an immunosuppressant effect.
Treatment with LAU-0901, a synthetic molecule that blocks pro-inflammatory platelet-activating factor, in addition to aspirin-triggered NPD1, reduced the size of damage areas in the brain, initiated repair mechanisms, and improved behavioral recovery following ischemic stroke.
Regulatory T cells expand in the first three weeks of life in breastfed babies, and are twice as abundant than in bottle-fed babies. Specifically, the bacterias Veillonella and Gemella are more abundant in the guts of breastfed babies. Veillonella and Gemella supportthe function of regulatory T cells.
Immune cells in the meninges monitor fluid released from the brain. If the fluid contains signs of infection, disease, or damage, the immune cells initiate an immune response to tackle the problem.
Study finds the immune system links personality to the long-term risk of mortality. Those who score higher on the personality trait of conscientiousness tend to live longer because their immune systems have lower levels of interleukin-6.
Study identifies 40 genes in mice that actively suppress axon regeneration in the central nervous system.
The protein Arginase-2 works through mitochondria to reduce inflammation. The findings could lead to new treatments for diseases associated with neuroinflammation, including multiple sclerosis and rheumatoid arthritis.
Chronic viral infections have a profound and lasting impact on the immune system in a similar way to aging. Chronic inflammation that occurs as a result of immune system dysregulation is often seen in diseases associated with aging.
Cysteine leukotriene receptor 2 appears to be a key player in chronic itch, a new study reports.
People with schizophrenia and other neuropsychiatric disorders may have a more permissive blood-brain barrier which allows the immune system to become more actively involved in the central nervous system. The resulting inflammation may contribute to the clinical manifestation of psychosis-like symptoms.
Study finds evidence of inflammation in the blood of patients during the early stages of Parkinson's disease. The findings support the theory that inflammation is a driver of the neurodegenerative disorder. The effect was most noticed in women with Parkinson's.