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IL-6

Featured Neurology Neuroscience Pain Psychology

·September 10, 2018·4 min read

Anger and Sadness May Cause Real Pain as Well as Being a Result of It

Exploring the relationship between emotion and pain in rheumatoid arthritis, researchers report emotions may function as a stressor, promoting inflammation and causing pain symptoms.

Featured Neuroscience Open Neuroscience Articles

·May 14, 2020·4 min read

Arthritis drug Anakinra may improve respiratory function in some patients with severe COVID-19

Anakinra, a clinically approved anti-inflammatory used to treat rheumatoid arthritis, improves respiratory function in patients with severe COVID-19 infection.

This shows someone holding a box of actemra

Featured Neurology Neuroscience

·May 3, 2020·2 min read

Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia

UCSD has launched a Phase III clinical trial to assess whether tocilizumab (Actemra), a drug commonly prescribed for rheumatoid arthritis and other inflammatory disorders, has therapeutic value for those at risk of developing severe COVID-19 infection. The drug is a monoclonal antibody-based therapy that blocks receptors for interleukin-6, a cytokine that triggers inflammation as an early immune response to coronavirus. Blocking IL-6 could prevent the risk of the COVID-19 associated cytokine storm many with severe infection experience.

Featured Neuroscience

·November 14, 2018·4 min read

Can’t Exercise? Taking a Hot Bath Improves Inflammation and Metabolism

For those who find it difficult to exercise, taking a hot bath can help improve inflammation and glucose levels, a new study reports.

Featured Neuroscience Open Neuroscience Articles

·May 20, 2020·3 min read

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

SARS-CoV-2, the virus responsible for COVID-19, enters human cells by attaching to ACE2 and utilizing TMPRSS2. Drugs that block ACE2 or inhibit the enzyme could help treat the coronavirus, but only during early infection. As the infection progresses, SARS-CoV-2 becomes engulfed in human cells, reducing the number of ACE2 receptors on a cell and leading to an increase of angiotensin II in the blood. Angiotensin II triggers an inflammatory pathway, providing a positive feedback cycle, named IL-6 amplifier, resulting in excessive immune activation and the cytokine storm associated with severe COVID-19.

Featured Neurology

·May 6, 2015·4 min read

Dopamine Could Play a Role in Promoting Chronic Pain

New findings could open the doors for the development of treatments for chronic pain.

Brain Cancer Featured Neurology Neuroscience

·November 26, 2021·4 min read

Drug Designed for Alzheimer’s Disease May Hold Promise for Treating Glioblastoma

A class of drugs called BACE1 inhibitors, originally designed to treat Alzheimer's disease, shows potential for the treatment of glioblastoma brain cancer.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 13, 2023·4 min read

Epilepsy Could Become Easier to Pinpoint With Blood Test

Higher levels of immune proteins are present in the blood both before and after an epileptic seizure. Researchers say the biomarkers can be identified via a simple blood test.

Featured Open Neuroscience Articles Psychology

·February 5, 2018·4 min read

Grape Derived Compounds May Promote Resilience Against Depression

Researchers have identified two compounds derived from grapes that might help to treat those with major depressive disorder.

Featured Neuroscience

·December 27, 2018·4 min read

How Exercise Reduces Belly Fat in Humans

According to researchers, interleukin 6 plays a critical role in how exercise helps to reduce body fat.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 18, 2018·6 min read

Immune Response May Trigger Chronic Fatigue Syndrome

Researchers report an exaggerated immune response can trigger chronic fatigue syndrome. The study reveals levels of Il-10 were higher in those who developed lasting fatigue, suggesting the immune system may have been primed to over respond.

Featured Neuroscience

·February 26, 2018·4 min read

Immune System Activation in Pregnant Women May Shape Developing Brain

A new study reveals immune system activation during pregnancy can have an impact on brain development in the offspring. Researchers report both short and long term brain function can be influenced by immune system activation during the third trimester.

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IL-6

Anger and Sadness May Cause Real Pain as Well as Being a Result of It

Arthritis drug Anakinra may improve respiratory function in some patients with severe COVID-19

Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia

Can’t Exercise? Taking a Hot Bath Improves Inflammation and Metabolism

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

Dopamine Could Play a Role in Promoting Chronic Pain

Drug Designed for Alzheimer’s Disease May Hold Promise for Treating Glioblastoma

Epilepsy Could Become Easier to Pinpoint With Blood Test

Grape Derived Compounds May Promote Resilience Against Depression

How Exercise Reduces Belly Fat in Humans

Immune Response May Trigger Chronic Fatigue Syndrome

Immune System Activation in Pregnant Women May Shape Developing Brain

Wasabi Compound Enhances Memory

Genes Associated with Earlier and Higher Reproduction Linked to Accelerated Aging

Novel Multiple Sclerosis Treatment Shows Promise

Brain’s Response to Crucial Language Hub Removal: New Insights

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