Researchers have implicated serotonin in the pathophysiology of RA.
M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.
Research seeks the 'master knob' to turn on nerve repair. Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.
People suffering from chronic itching as a result of a condition called chronic idiopathic pruritus found some symptom relief after taking a drug designed to treat rheumatoid arthritis, researchers report.
