Older adults who suffer from hypothyroidism are at increased risk of developing dementia. The risk is even higher in those who require thyroid hormone replacement therapy to treat their condition.
Hyperthyroidism causes the amygdala and hippocampus to shrink when hormone levels are high, but when hormone levels subside, symptoms reduce and the brain areas resume their normal size.
Maternal hypothyroidism may contribute to an increased risk of ADHD in their offspring.
A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.
