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Huntington’s disease

This shows a muscle cell of a long-lived nematode worm.

Featured Genetics

·May 8, 2015·3 min read

New Role Idenitified for Protein Aggregates in Neurodegeneration

According to a new study, the proteome undergoes extensive changes during aging.

Featured Genetics Open Neuroscience Articles

·June 2, 2016·4 min read

New Ways to Protect Against Neurodegeneration

NMNAT2 may protect against the debilitating effects of some neurodegenerative diseases, including Alzheimer's disease.

Brain image with the basal ganglia and other brain areas.

Featured Neuroscience

·January 30, 2013·2 min read

NIH Study Advances Understanding of Movement Control

Voluntary movements involve the coordinated activation of two brain pathways that connect parts of deep brain structures called the basal ganglia, according to a study in mice.

This shows huntingtin protein aggregates.

Featured Neurology

·April 23, 2015·3 min read

Novel Regulator Inhibits Toxic Protein Aggregates in Huntington’s Disease

Researchers discover a novel factor which suppresses misfolding and aggregation of the huntingtin protein.

Image shows a diagram explaining apoptosis.

Featured Genetics Neurology

·November 22, 2016·3 min read

Novel Type of Cell Death in Huntington’s Disease May Lead to Effective New Therapies

Researchers have identified a novel type of cell death associated with Huntington's disease.

Featured Neuroscience Open Neuroscience Articles

·February 15, 2016·4 min read

Observing Brain Diseases in Real Time

Researchers use an innovative new tool to observe protein aggregation throughout the life cycle of a worm.

Featured Genetics Neurology Open Neuroscience Articles

·February 26, 2018·3 min read

One Step Closer to Treatment for Huntington’s

A new study reports researchers have developed a new gene editing approach that may provide a new treatment avenue for Huntington's disease.

Featured Neurology Neuroscience

·June 13, 2023·6 min read

Pathway to Treat Huntington’s & Amyloid Diseases Identified

Researchers identified the structure of the nucleus, the first step in amyloid formation associated with neurodegenerative diseases like Huntington’s. The study suggests a radical method to treat these diseases—halting the initial amyloid formation step.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 20, 2012·3 min read

Proposed Drug May Reverse Huntington’s Disease Symptoms

Single treatment produces long-term improvement in animal models. With a single drug treatment, researchers at the Ludwig Institute for Cancer...

Featured Genetics Neurology Open Neuroscience Articles

·September 14, 2016·4 min read

Protecting Nerve Cells From Huntington’s Disease

Researchers have discovered a way in which it could be possible to stop proteins from triggering energy failure inside nerve cells in those affected by Huntington's disease.

Featured Neurology

·January 18, 2011·2 min read

Protein Misfolding and Aggregation Roles in Neurodegenerative Diseases

Max Planck researchers discovered that large, less hydrophobic proteins with a significant increase of disorder in their structures were more...

Image shows striatal neurons from a patient with huntington's disease.

Featured Genetics Neurology

·September 5, 2016·3 min read

Protein Subunit Found to Rescue Afflicted Neurons in Huntington’s Disease

Researchers use a novel co-culturing method to create functional circuits that model Huntington's disease and find new clues to potential treatment approaches.

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