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Huntington’s disease

This is an illustration of a male Drosophila melanogaster.

Featured Genetics Open Neuroscience Articles

·September 18, 2013·2 min read

Shining Light on Neurodegenerative Pathway

Researchers have identified a possible molecular pathway which could be the of cause a number of neurodegenerative diseases, including Huntington's disease and ALS.

The image shows the immunohistochemical detection of the neuronal marker. The caption best describes the image.

Featured Genetics Open Neuroscience Articles

·October 9, 2013·3 min read

Single Gene Mutation Linked to Diverse Neurological Disorders

A gene mutation which causes Lesch-Nyhan syndrome could provide clues to the developmental and neurological defects noted in other neurodegenerative diseases.

The image shows the dual yeast and stem cell platform. The caption best describes the image.

Featured Neurology

·October 24, 2013·5 min read

Yeast, Human Stem Cells Drive Discovery of New Parkinson’s Disease Drug Targets

Researchers have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson’s patients.

These slides show the comparison morphographies associated with the research.

Featured Genetics Open Neuroscience Articles

·December 11, 2013·3 min read

Staying Ahead of Huntington’s Disease

Researchers work to understand how expanded polyglutamine tracts form the types of supramolecular structures that are presumed to be toxic to neurons.

Featured Neuroscience Open Neuroscience Articles

·December 29, 2013·2 min read

Research into Axon Degeneration Hits a Nerve

Researchers identify a gene which protects against spontaneous, adult onset progressive neurodegeneration.

This image shows the basal ganglia with specific areas labeled.

Featured Neuroscience

·April 8, 2014·2 min read

What Songbirds Tell Us About How We Learn

According to new research, the basal ganglia plays an important role for vocal learning across different species.

Featured Neuroscience Psychology

·May 27, 2014·2 min read

‘Sticky Synapses’ Can Impair New Memories by Holding on to Old Ones

Researchers discover so-called sticky synapses can impair new learning by excessively hard wiring old memories.

This image shows a the researchers looking at their data on a computer screen.

Featured Neurology Open Neuroscience Articles

·June 6, 2014·4 min read

Brain Traffic Jams That Can Disappear in 30 Seconds

Cellular blockages in fruit fly's neurons can form and dissolve in 30 seconds or less, a new study reports. The findings could help pave the way for new treatments of some neurodegenerative disorders.

The image shows a brain slice from 5 week old mice with htt.

Featured Neurology

·July 9, 2014·4 min read

Huntington’s Disease Protein Helps Wire the Young Brain

The Htt protein, which is mutated in Huntington's disease patients, is critical for wiring the brain in early life, a new study reports.

This image shows a scheme of the generation of induced pluripotent stem (iPS) cells.

Featured Genetics Neurology Open Neuroscience Articles

·September 5, 2014·2 min read

Disease in a Dish Approach Could Aid Huntington’s Disease Discovery

Researchers use iPSCs to create a disease in a dish model of Huntington's disease in transgenic nonhuman primates.

The image shows autophagia in the cells.

Featured Neurology

·September 8, 2014·2 min read

Broken Signals Lead to Neurodegeneration

Researchers discover the IP3R receptor can be locked into closed state by enzyme action. This could potentially play a role in the reduction of neuron signaling seen in some neurodegenerative disorders.