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Huntington’s disease

The image shows a brain slice from 5 week old mice with htt.

·July 9, 2014·4 min read

Huntington’s Disease Protein Helps Wire the Young Brain

The Htt protein, which is mutated in Huntington's disease patients, is critical for wiring the brain in early life, a new study reports.

Featured Genetics Neurology Open Neuroscience Articles

·June 7, 2016·5 min read

Slowing Huntington’s by Swapping Sick for Healthy Brain Cells: Mouse Study

By transplanting healthy glial cells, researchers have succeeded in reducing the symptoms and slowing the progression of Huntington's disease in mice.

Image shows striatal neurons from a patient with huntington's disease.

Featured Genetics Neurology

·September 5, 2016·3 min read

Protein Subunit Found to Rescue Afflicted Neurons in Huntington’s Disease

Researchers use a novel co-culturing method to create functional circuits that model Huntington's disease and find new clues to potential treatment approaches.

Featured Genetics Neurology

·April 13, 2018·5 min read

Excess of Mitochondrial Iron Linked to Huntington’s Disease

Researchers have identified an over accumulation of iron in the mitochondria of mice genetically engineered to have Huntington's disease.

Featured Genetics Neurology Neuroscience

·December 12, 2022·4 min read

CRISPR Technology Improves Huntington’s Disease Symptoms in Models

Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.

Featured Neurology Neuroscience

·May 18, 2011·3 min read

Neutrons Provide First Sub-nanoscale Snapshots of Huntington’s Disease Protein

Energy’s Oak Ridge National Laboratory and the University of Tennessee have for the first time successfully characterized the earliest structural...

The image shows a single striatal neuron (yellow) transfected with nuclear inclusion (orange) mHtt, other neurons in background (blue).

Featured Genetics Neurology

·January 5, 2015·4 min read

Animal Study Points to a Treatment for Huntington’s Disease

Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.

Featured Neurology Neuroscience

·September 19, 2022·3 min read

Discovery of the Causes of Brain Dysfunction in Patients With Huntington’s Disease

Researchers discovered decreased function in a protein critical for synaptic function in those with Huntington's disease.

Featured Genetics Neurology Open Neuroscience Articles

·February 26, 2018·3 min read

One Step Closer to Treatment for Huntington’s

A new study reports researchers have developed a new gene editing approach that may provide a new treatment avenue for Huntington's disease.

This is an illustration of a male Drosophila melanogaster.

Featured Genetics Open Neuroscience Articles

·September 18, 2013·2 min read

Shining Light on Neurodegenerative Pathway

Researchers have identified a possible molecular pathway which could be the of cause a number of neurodegenerative diseases, including Huntington's disease and ALS.