FeaturedNeurologyNeuroscience Videos·June 27, 2012·3 min readNerve Pathway for Combating Axon Injury and Stress May Hold Benefits for Individuals With Neurodegenerative DisordersResearchers from the Huck Institutes’ Center for Cellular Dynamics, led by Center director Melissa Rolls, have found that a neuroprotective...Read More
FeaturedGeneticsNeurology·June 28, 2012·3 min readHuman Model of Huntington’s Disease Created from Skin’s Stem Cells‘HD in a dish’ will facilitate search for elusive treatment. An international consortium of Huntington’s disease experts, including several from...Read More
FeaturedGeneticsNeurology·July 11, 2012·3 min readTwo Proteins Offer a Clearer Way to Treat Huntington’s DiseaseHD mice crossbred with mice that produced greater levels of PGC-1alpha showed dramatic improvement. Production of misfolded proteins was essentially eliminated and the mice behaved normally. “Degeneration of brain cells is prevented. Neurons don’t die,” said La Spada.Read More
FeaturedNeurology·September 17, 2012·3 min readToxic Protein Build-up in Blood Shines Light on Fatal Brain DiseaseA new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells.Read More
Genetics·September 18, 2012·1 min readNew Findings on Protein MisfoldingResearchers identified 21 proteins that specifically bind to a protein called ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures, whereas nine of them prevent the misfolding.Read More
FeaturedNeuroscience·January 30, 2013·2 min readNIH Study Advances Understanding of Movement ControlVoluntary movements involve the coordinated activation of two brain pathways that connect parts of deep brain structures called the basal ganglia, according to a study in mice.Read More
FeaturedGenetics·February 26, 2013·5 min readResearchers Find Controlling Element of Huntington’s DiseaseResearchers discover a three molecule complex could be a target for treating Huntington's Disease, a genetic and currently incurable brain disease which causes movement disorders and dementia.Read More
FeaturedGenetics·June 6, 2013·5 min readScientists Coax Brain to Regenerate Cells Lost in Huntington’s DiseaseResearchers mobilize the brain's native stem cells to replenish medium spiny neurons which are lost in Huntington's disease.Read More
FeaturedNeuroscience·June 7, 2013·4 min readResearchers Focus on a Brain Protein and an Antibiotic to Block Cocaine CravingA new study shows that the GLT1 protein plays a critical role in the craving for cocaine which develops after only a few days of cocaine use. However, exposure to ceftriaxone, an antibiotic used to treat meningitis, decreases cocaine cravings.Read More
FeaturedNeurologyNeuroscience Videos·June 28, 2013·5 min readScientists View ‘Protein Origami’ to Help Understand, Prevent Certain DiseasesUsing sophisticated imaging techniques, researchers observe a molecular protein folding process which could help better understand and treat neurodegenerative diseases and cancers.Read More
FeaturedNeurology·July 21, 2013·5 min readFor a Healthy Brain, Don’t Let the Trash Pile UpA new study indicates that quickly clearing away defective proteins in the brain could help prevent some neurodegenerative disorders.Read More
FeaturedNeurologyOpen Neuroscience Articles·July 29, 2013·3 min readEssential Clue to Huntington’s Disease Solution FoundResearchers have developed a new way in which to measure the shape of the huntingtin protein in living cells.Read More
