Researchers discovered some protease inhibitors used to treat HIV can lead to the production of the peptide amyloid beta.
HIV infection leads to increased EIF2 signaling in microglia, astrocytes, and neurons. Study reveals how HIV infection and some antiretrovirals affect cognition and the central nervous system.
A new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.
