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gut-brain axis

Featured Genetics Neuroscience Open Neuroscience Articles

·April 29, 2020·5 min read

Scientists explore links between genetics, gut microbiome and memory

Researchers have honed in on a link between genetics, the gut microbiome, and memory. A new study identified a lactate as a key memory-boosting molecular messenger in mouse models. Mice fed Lactobacillus microbes had increased levels of GABA in their brains.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.

Featured Neuroscience

·April 15, 2020·4 min read

A gut-to-brain circuit drives sugar preference and may explain sugar cravings

Sweet tasting foods don't only trigger the taste buds, they also switch on a neurological pathway that begins in the gut. In the intestines, signals of sugar ingestion travel to the brain, sparking an appetite for more sweet foods. However, this pathway only responds to sugars, not artificial sweeteners.

Featured Neuroscience

·April 6, 2020·6 min read

Newly identified digestive-brain axis controls food choice

Study reveals a novel learning process orchestrated between the digestive system and brain that compels animals to seek out novel foods.

Featured Neurology Neuroscience

·February 18, 2020·5 min read

Parkinson’s biomarker may originate in gut

Using mouse models, researchers seeded alpha-synuclein aggregates in gut neurons and discovered the clumps can travel to neurons in the brain.

Featured Neurology Neuroscience

·January 8, 2020·4 min read

Gut microbes may improve stroke recovery

Microbiota-derived short-chain fatty acids (SCFA) modulate stroke recovery. The effect was mediated by circulating lymphocytes on microglia activation. The study reports SCFAs could be a potential therapeutic to improve post-stroke recovery.

Featured Genetics Neurology Neuroscience

·January 3, 2020·6 min read

Fat-dissolving bile acids may help regulate gut immunity and inflammation

Two studies reveal the role bile acids play in immunity and inflammation.

Featured Neurology Neuroscience

·January 2, 2020·2 min read

Harnessing the microbiome to improve stroke recovery

Short-chain fatty acid supplementation improves stroke recovery in mouse models.

This shows a skeleton and a computer screen with a brain on it

Featured Neurology Neuroscience

·December 4, 2019·3 min read

The gut may be involved in the development of multiple sclerosis

Increased levels of Smad7 in T-cells is linked to multiple sclerosis-like symptoms in mice. In the intestines, the T-cells were more frequently activated and migrated to the central nervous system, where they triggered inflammation. Similar activation was seen in human patients with multiple sclerosis. The findings provide further evidence that multiple sclerosis may start in the intestines and spread via the CNS.

Featured Neurology Neuroscience Open Neuroscience Articles

·November 14, 2019·5 min read

Inflammatory bowel disease appears to impact risk of Parkinson’s disease

Study provides new insights into how the immune system and inflammation play a role in the development and progression of Parkinson's disease.

Featured Neuroscience Open Neuroscience Articles

·November 14, 2019·4 min read

Bacteria in the gut may alter aging process

Transplanting gut microbiota from older mice to younger germ-free mice increased hippocampal neurogenesis and intestinal growth.

This shows the outline of two bodies. One has the head highlighted red, the other has the gut highlighted red

Featured Neurology Neuroscience Open Neuroscience Articles

·November 7, 2019·4 min read

Where does Parkinson’s disease start? In the brain or gut? Or both?

Lewy body disorders, including Parkinson's disease and Lewy body dementia, comprise of two distinct subtypes. One subtype originates in the peripheral nervous system (PNS) of the gut and spreads to the brain. The other originates in the brain, or enters the brain via the olfactory system, before spreading to the brainstem and PNS.

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gut-brain axis

Scientists explore links between genetics, gut microbiome and memory

More evidence Parkinson’s disease may start in the gut

A gut-to-brain circuit drives sugar preference and may explain sugar cravings

Newly identified digestive-brain axis controls food choice

Parkinson’s biomarker may originate in gut

Gut microbes may improve stroke recovery

Fat-dissolving bile acids may help regulate gut immunity and inflammation

Harnessing the microbiome to improve stroke recovery

The gut may be involved in the development of multiple sclerosis

Inflammatory bowel disease appears to impact risk of Parkinson’s disease

Bacteria in the gut may alter aging process

Where does Parkinson’s disease start? In the brain or gut? Or both?

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