FeaturedNeurologyNeuroscience·February 22, 2021·4 min readTarget for Stroke Therapy in Blood-Brain Barrier DiscoveredThe stroke byproduct acrolein activates the precursor of heparanase, an enzyme that degrades the glycocalyx in the blood-brain barrier.Read More
FeaturedNeuroscience·April 22, 2019·5 min readSugar entering the brain during septic shock causes memory lossDuring sepsis, the body sheds fragments of heparan sulfate, which crossed the blood-brain barrier and enters the hippocampus. The presence of heparan sulfate in the hippocampus may cause memory loss associated with septic shock.Read More