Ketamine's antidepressant effect is a result of the enhancement of Kcnq2 potassium channels in a certain subtype of glutamate-sensitive neurons.
Glutamate binds to the subunits of its receptor only in specific patterns. The findings upend previous belief that each subunit binds glutamate independently and points to a new level of complexity in neurotransmission and drug response.
Researchers investigate how cannabis can influence a number of cognitive and psychological processes.
Study reveals a new role for a scaffolding molecule that appears to play a part in glutamate receptor transportation and ultimately, memory formation.
Just one protein situated on the synapse can profoundly alter how some neurons communicate and implement plasticity.
A new study found a person's math ability was linked to levels of GABA and glutamate in the brain. In children, greater math fluency was associated with higher GABA levels in the left intraparietal sulcus, while lower levels of GABA were linked to math ability in adults. The reverse was true for glutamate in both children and adults.
Study provides a broader understanding of light's ability to break chemical bonds and release active molecules.
Glutamate is first released near the AMPA-type glutamate receptors, then released near the NMDA-type receptors immediately after the first signal to activate the switch for synaptic plasticity.
Plumes of glutamate in the brain could explain the onset of migraines with auras, a new study reports.
Low-level exposure to lead during development does not lead to alcohol use disorder, but does alter the neural circuits in a way that if addiction occurs, it makes it harder to refrain from returning to addiction related behaviors.
The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
The key to performance and motivation lies within the ratio of glutamine and glutamate in the nucleus accumbens. The ratio of glutamine to glutamate relates specifically to stamina.
