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GLP-1

·June 27, 2024·3 min read

Ozempic Boost Fullness Pre-Meal via Hypothalamus

A new study shows GLP-1 receptor agonists increase pre-meal fullness by activating neurons in the dorsomedial hypothalamus. This mechanism helps prevent overeating, offering insights into obesity treatment. The research highlights how GLP-1 impacts food perception and hypothalamic responses to food cues, enhancing satiation before food intake.

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Featured Neurology Neuroscience

·June 21, 2024·4 min read

Ozempic May Reduce Alzheimer’s Risk

GLP-1 agonists like Ozempic reduce the risk of dementia in type 2 diabetes patients. The research followed over 88,000 individuals for up to ten years, showing a 30% lower risk compared to sulfonylureas and a 23% lower risk compared to DPP-4 inhibitors. These findings can guide doctors in selecting medications for older diabetes patients. However, further randomized trials are needed to confirm these results.

Featured Neuroscience Psychology

·June 3, 2024·3 min read

Ozempic May Reduce Alcohol Abuse Risk

Diabetes drugs Wegovy and Ozempic, containing semaglutide, significantly reduce the incidence and recurrence of alcohol-use disorder (AUD). Analyzing health records, researchers observed a 50% to 56% decrease in AUD among patients treated with semaglutide.

Featured Neuroscience

·May 16, 2024·6 min read

GLP-1 and NMDA Targeted Weight-Loss Drug Shows Promise

Researchers have developed a novel weight-loss drug that combines GLP-1 with molecules targeting NMDA receptors in the brain. This "Trojan Horse" approach allows the drug to specifically target the appetite control center, leading to significant weight loss in mice.

Featured Neuroscience

·November 24, 2023·6 min read

Taste, Not Stomach, Regulates Eating Habits

A new study challenges the traditional understanding of appetite control. The research reveals that our sense of taste, rather than signals from the stomach, plays a critical role in regulating how much we eat.

Featured Neuroscience

·January 12, 2019·4 min read

Bile Acids Mediate Metabolic Benefits of Weight Loss Surgery

Researchers report bile acids play a key role in providing positive metabolic effects after weight loss surgery. The study also suggest the intestinal microbiome participates in post surgical improvements following gastric bypass. The findings could help develop new treatments for diabetes and obesity, researchers report.

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Featured Neurology Open Neuroscience Articles

·January 2, 2018·4 min read

Diabetes Drug ‘Significantly Reverses Memory Loss’ in Alzheimer’s: Mouse Study

Lancaster University researchers report a drug developed to treat diabetes shows promise in reversing memory loss associated with Alzheimer's in mouse models of the disease. The drug appears to have a neuroprotective effect, enhancing brain growth factors while reducing amyloid plaques, chronic inflammation and oxidative stress. The drug also slows down the rate of neuron loss.

Featured Neuroscience

·November 24, 2015·4 min read

Gut Microbes Signal to the Brain When They Are Full

According to a new study, twenty minutes after a meal, gut microbes produce proteins that suppress the desire for feeding in animals.

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Featured Genetics Open Neuroscience Articles

·July 26, 2015·4 min read

Eat For Pleasure Rather Than Hunger? You May Have a Hormone Deficiency

Do you prefer the taste of fatty food? Are you someone who eats for pleasure rather than for hunger's sake? According to a new study, the tendency to overeat could be due to a hormone deficiency.