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GLP-1

·January 12, 2019·4 min read

Bile Acids Mediate Metabolic Benefits of Weight Loss Surgery

Researchers report bile acids play a key role in providing positive metabolic effects after weight loss surgery. The study also suggest the intestinal microbiome participates in post surgical improvements following gastric bypass. The findings could help develop new treatments for diabetes and obesity, researchers report.

Featured Neuroscience Psychology

·July 29, 2026·8 min read

Oral Ozempic Cuts Heavy Drinking and Cravings

Oral semaglutide reduces heavy drinking days, daily cravings, and alcohol-related problems in adults with Alcohol Use Disorder.

This shows the outline of a person and a brain.

Featured Neuroscience

·January 20, 2025·6 min read

GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks

A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including reduced risks of addiction, Alzheimer’s, and dementia. However, they also pose risks for pancreatitis and kidney conditions, emphasizing the need for careful monitoring.

Featured Neuroscience

·June 27, 2024·3 min read

Ozempic Boost Fullness Pre-Meal via Hypothalamus

A new study shows GLP-1 receptor agonists increase pre-meal fullness by activating neurons in the dorsomedial hypothalamus. This mechanism helps prevent overeating, offering insights into obesity treatment. The research highlights how GLP-1 impacts food perception and hypothalamic responses to food cues, enhancing satiation before food intake.

This shows a brain surrounded by faded foods, as though the foods represent distant memories.

Featured Neuroscience

·February 12, 2026·7 min read

Memory of Food: Brain Circuits Control Appetite Through Context

Forget the "willpower" myth, new research suggests that your past experiences are the real secret to appetite control. By identifying a hidden circuit that links memory to hunger, scientists have discovered how the brain uses your environment to decide when it's time to eat, and how a "glitch" in this system leads to overeating.

Featured Genetics Neuroscience

·July 15, 2024·5 min read

Adjusting Proteins Increases Ozempic’s Effectiveness

Adjusting melanocortin proteins in the brain enhances the effectiveness of GLP-1 diabetes and weight-loss drugs. By inhibiting MC3R or activating MC4R, mice showed increased sensitivity to these drugs, leading to more significant weight loss and reduced feeding without additional side effects.

Image shows trees cut to look like heads.

Featured Neurology Open Neuroscience Articles

·January 2, 2018·4 min read

Diabetes Drug ‘Significantly Reverses Memory Loss’ in Alzheimer’s: Mouse Study

Lancaster University researchers report a drug developed to treat diabetes shows promise in reversing memory loss associated with Alzheimer's in mouse models of the disease. The drug appears to have a neuroprotective effect, enhancing brain growth factors while reducing amyloid plaques, chronic inflammation and oxidative stress. The drug also slows down the rate of neuron loss.

This shows a woman holding her head in pain.

Featured Neurology Neuroscience

·March 2, 2026·7 min read

Beyond Weight Loss: Ozempic Linked to Migraine Reduction

Unexpected relief. New research shows that patients taking GLP-1 drugs for diabetes or weight loss also experience fewer emergency room visits and need fewer medications for their chronic migraines.

This shows a brain and pills. One half of the brain is red, implying violence.

Featured Neuroscience Psychology

·June 17, 2026·8 min read

Can GLP-1 Medications Blunt the Path to Violence?

GLP-1 receptor agonists, such as Ozempic and Wegovy, may drastically reduce behaviors linked to violence.

Featured Neuroscience

·November 24, 2015·4 min read

Gut Microbes Signal to the Brain When They Are Full

According to a new study, twenty minutes after a meal, gut microbes produce proteins that suppress the desire for feeding in animals.

Featured Neuroscience Visual Neuroscience

·July 14, 2026·10 min read

GLP-1s Linked to Sudden, Rare Vision Loss

Researchers identifies a slight statistical association between GLP-1 receptor agonists (including semaglutide and tirzepatide) and an increased risk of ischemic optic neuropathy.

Featured Neuroscience

·May 16, 2024·6 min read

GLP-1 and NMDA Targeted Weight-Loss Drug Shows Promise

Researchers have developed a novel weight-loss drug that combines GLP-1 with molecules targeting NMDA receptors in the brain. This "Trojan Horse" approach allows the drug to specifically target the appetite control center, leading to significant weight loss in mice.

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GLP-1

Bile Acids Mediate Metabolic Benefits of Weight Loss Surgery

Oral Ozempic Cuts Heavy Drinking and Cravings

GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks

Ozempic Boost Fullness Pre-Meal via Hypothalamus

Memory of Food: Brain Circuits Control Appetite Through Context

Adjusting Proteins Increases Ozempic’s Effectiveness

Diabetes Drug ‘Significantly Reverses Memory Loss’ in Alzheimer’s: Mouse Study

Beyond Weight Loss: Ozempic Linked to Migraine Reduction

Can GLP-1 Medications Blunt the Path to Violence?

Gut Microbes Signal to the Brain When They Are Full

GLP-1s Linked to Sudden, Rare Vision Loss

GLP-1 and NMDA Targeted Weight-Loss Drug Shows Promise

Resource Scarcity Alters Maternal Brain Activity to Hinder Caregiving

Existing Drug Could Halt Brain Inflammation in Alzheimer’s

Ultraprocessed Foods Alter Insulin and Brain Reward Responses

Optogenetics Pioneers Win 2026 Nobel Prize in Physiology or Medicine

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