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glioblastoma

Brain Cancer Featured Genetics Neurology Neuroscience

·July 19, 2019·6 min read

Study hints at why an aggressive form of brain cancer is hard to treat

Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively.

This shows macrophages in GBM tissue samples

Brain Cancer Featured Neurology Neuroscience

·June 25, 2019·4 min read

Scientists track brain tumor turncoats with advanced imaging

Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 10, 2019·5 min read

Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·May 30, 2019·4 min read

Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice

Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 11, 2019·4 min read

Shutting down deadly pediatric brain cancer at its earliest moments

Dysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.

This image shows a syringe and medical paper work

Brain Cancer Featured Neurology Neuroscience

·March 31, 2019·4 min read

New glioblastoma vaccine shows promising results in phase Ib clinical trial

A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.

Brain Cancer Featured Genetics Neurology Neuroscience

·February 11, 2019·5 min read

Immunotherapy Can Be Effective in Treating People with Recurrent Glioblastoma

Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.

Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 25, 2019·4 min read

The Hitchhiker’s Guide to Defeating Glioblastoma

Researchers have developed a new approach that uses microRNA in combination with chemotherapy to help treat glioblastoma brain cancer. In preclinical models, the approach increases survival of the deadly brain cancer five fold.

Featured Genetics Neurology Neuroscience

·January 20, 2019·3 min read

Evaluating the Effects of Environmental Exposures on Neurological Disorders

Researchers have identified a number of environmental factors, including the herbicide Linuron, as inflammation activators in neurodegenerative disorders.

Brain Cancer Featured Genetics Neurology Neuroscience

·January 11, 2019·6 min read

A Patient’s Sex Matters When it Comes to Brain Cancer

Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·January 10, 2019·4 min read

How Drugs Can Minimize the Side Effects of Chemotherapy

Researchers have identified the 3D structure of a brain receptor that causes vomiting and nausea as a result of chemotherapy treatments for cancer. The same receptor also plays a critical role in pain perception, migraines and chronic itching.