An oncogene believed to be responsible for glioblastoma brain cancer has been identified. AVIL, a gene that normally helps cells to maintain their shape and size, can shift into overdrive, causing cancer cells to form and spread. Blocking the gene's activity completely destroyed glioblastoma cancer cells in mouse models, but did not have any effect on healthy cells. The findings provide potential new treatment avenues for the deadly brain cancer. Read More
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models. Read More
Researchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients. Read More
Researchers discover an enzyme, IDH, which facilitates the breakdown of specific amino acids makes glioblastoma brain cancer particularly aggressive. Read More
New findings could provide additional insight into the cause of glioblastoma and provide new options for personalized therapeutic treatments. Read More
Human glioma brain tumor cell growth was halted and erased in mice, according to new research. Read More
Researchers report an experimental treatment has shown to be able to stop treatment resistant glioblastoma in human cells and mouse models. Read More
According to a new study, elevated levels of the NHE9 protein can add to the lethality of glioblastoma brain cancer. Read More
Researchers have identified a pathway by which glioblastoma cancer cells aggressively spread and grow in the brain. Read More
A new study reports a genetically modified poliovirus therapy has been shown to improve long term survival rates in recurrent glioblastoma brain cancer patients. Researchers say the therapy had a three year survival rate for 21 percent of participants in a phase 1 clinical trial, compared to just 4% of patients who received more standard treatments. Read More
When aggressive, malignant tumors appear in more than one location in the brain, patient survival tends to be significantly shorter than when the disease starts as a single tumor, even though patients in both groups undergo virtually identical treatments, according to research at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Research Institute. Read More
An experimental nanotechnology drug crosses the blood-brain barrier and targets brain tumor cells, a new study suggests. The drug also blocks the growth of tumor blood vessels. Read More