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glioblastoma

Brain Cancer Featured Neurology Neuroscience

·October 3, 2025·7 min read

Glioblastoma Found to Erode Skull and Hijack Immune System

Glioblastoma, the most lethal brain cancer, doesn’t just damage the brain—it erodes the skull and disrupts the immune system by reshaping marrow inside the skull. Researchers discovered that tumors increase skull-to-brain channels, allowing waves of inflammatory immune cells to flow to the cancer site, fueling its growth.

Brain Cancer Featured Neurology Neuroscience

·September 18, 2025·6 min read

When Brain Cancer Cells Stick Together, They’re Less Dangerous

A groundbreaking study has revealed that glioblastoma cells behave differently depending on whether they cluster or disperse. Cells that remain in clusters are less aggressive, while dispersed cells are more plastic, meaning they can adapt and resist treatments more easily.

Brain Cancer Featured Genetics Neurology Neuroscience

·September 8, 2025·6 min read

Hidden DNA Loops Linked to Early Spread of Brain Cancer

Scientists have discovered that rogue DNA rings, called extrachromosomal DNA (ecDNA), appear early in glioblastoma and drive its rapid growth and resistance to therapy. By combining patient data, imaging, and computational modeling, researchers found that ecDNA often carries the EGFR cancer gene and its aggressive variants.

Brain Cancer Featured Neuroscience

·September 4, 2025·8 min read

Dietary Intervention Could Slow Deadly Brain Cancer Growth

A new study reveals that glioblastoma, the most aggressive brain cancer, thrives by using sugar in unique ways that differ from healthy brain cells. While normal brain tissue channels sugar into energy and neurotransmitters, glioblastoma cells divert it into producing DNA and RNA, fueling relentless tumor growth.

Brain Cancer Featured Neurology Neuroscience

·September 2, 2025·5 min read

Freezing Brain Molecules Could Halt Deadly Cancer Spread

Scientists have identified a new way to stop glioblastoma — the deadliest form of brain cancer — from spreading by altering its environment rather than targeting the tumor directly. The team showed that cancer cells depend on flexible hyaluronic acid molecules to invade surrounding brain tissue, but when these molecules were "frozen," cells became immobile and dormant.

Brain Cancer Featured Genetics Neurology Neuroscience

·May 30, 2025·6 min read

Lab-Designed Peptide Targets Glioblastoma Stem Cells

A newly developed lab-designed molecule, JM2, may offer a promising therapy to combat glioblastoma recurrence by targeting the tumor’s most resilient cells. Researchers discovered that glioblastoma stem cells rely on the protein connexin 43’s interaction with microtubules—an interaction disrupted by JM2.

Brain Cancer Featured Neurology Neuroscience

·May 15, 2025·4 min read

Gabapentin Linked to Longer Survival in Glioblastoma Brain Cancer

A new study suggests that gabapentin, a widely used anti-seizure medication, may improve survival in patients with glioblastoma (GBM), the deadliest form of brain cancer. Researchers found that GBM patients taking gabapentin lived several months longer than those who did not, across two independent hospital datasets.

Brain Cancer Featured Genetics Neurology Neuroscience

·May 12, 2025·6 min read

Mapping the Cellular Secrets of Glioblastoma

Two landmark studies have mapped the complex cellular ecosystems of glioblastoma, the deadliest form of brain cancer, offering unprecedented insights into how its diverse cells evolve and resist treatment. Using single-cell RNA sequencing on over 430,000 cells from 59 patients, researchers identified three new glioblastoma cell states and classified tumors into three overarching cellular ecosystems.

Brain Cancer Featured Neurology Neuroscience

·May 9, 2025·3 min read

Glioblastoma Vaccine Trial Moves Forward

The phase 2B SURVIVE trial testing SurVaxM, a cancer vaccine for glioblastoma, will continue as planned following an interim analysis showing sufficient promise to proceed. SurVaxM, combined with standard treatments like surgery, radiation, and chemotherapy, aims to extend survival and improve quality of life for patients with this aggressive brain cancer.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 22, 2025·6 min read

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

A new study reveals that the way DNA folds inside brain cells plays a critical role in glioblastoma, one of the deadliest forms of brain cancer. Researchers discovered that in cancer cells, genes cluster into 3D "hubs" that coordinate tumor-driving activity, even without mutations.

Autism Brain Cancer Featured Genetics Neuroscience

·January 9, 2025·8 min read

Youthful Brain Stem Cells Linked to Autism and Brain Cancer

Researchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma. These stem cells show gene expression patterns that regulate early brain development and, when disrupted, could lead to neurological conditions.

Brain Cancer Featured Neurology Neuroscience

·December 12, 2024·8 min read

Glioblastoma Syncs With the Body’s Internal Clock

Glioblastoma, an aggressive brain cancer, syncs its internal clock to the host’s circadian rhythms, leveraging daily hormone cycles for growth. Blocking these signals slowed tumor progression in mice and revealed that the timing of treatments like dexamethasone (DEX) critically influences outcomes.

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glioblastoma

Glioblastoma Found to Erode Skull and Hijack Immune System

When Brain Cancer Cells Stick Together, They’re Less Dangerous

Hidden DNA Loops Linked to Early Spread of Brain Cancer

Dietary Intervention Could Slow Deadly Brain Cancer Growth

Freezing Brain Molecules Could Halt Deadly Cancer Spread

Lab-Designed Peptide Targets Glioblastoma Stem Cells

Gabapentin Linked to Longer Survival in Glioblastoma Brain Cancer

Mapping the Cellular Secrets of Glioblastoma

Glioblastoma Vaccine Trial Moves Forward

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

Youthful Brain Stem Cells Linked to Autism and Brain Cancer

Glioblastoma Syncs With the Body’s Internal Clock

Animal-Free Brain Tissue Breakthrough Could Transform Drug Testing

Next-Gen Wearable Lets You Control Machines with Simple Gestures

Quitting Impossible Goals May Actually Boost Wellbeing

How Mounjaro Alters Craving Circuits in the Brain

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