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Genetics

·July 16, 2012·2 min read

Gene Therapy Treatment Extends Lives of Mice with Fatal Disease, Spinal Muscular Atrophy

Mice born with Spinal Muscular Atrophy typically only live five to six days. University of Missouri researchers introduced the SMN gene into the mice’s central nervous systems and were able to extend their lives 10-25 days longer.

Featured Genetics Neuroscience

·July 16, 2012·3 min read

Neurons Derived from Cord Blood Cells May Represent New Therapeutic Option

The researchers demonstrated that cord blood cells, which come from the mesoderm, the middle layer of embryonic germ cells, can be switched to ectodermal cells, outer layer cells from which brain, spinal and nerve cells arise. "This study shows for the first time the direct conversion of a pure population of human cord blood cells into cells of neuronal lineage by the forced expression of a single transcription factor," says Juan Carlos Izpisua Belmonte.

Electrophysiology Featured Psychology

·July 11, 2012·7 min read

Why the Thrill is Gone: Scientists Identify Potential Target for Treating Major Symptom of Depression

Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new antidepressants.

Featured Genetics Neurology

·July 11, 2012·3 min read

Gene Link to Multiple Sclerosis Explains Drug Side Effects

The biological role of a gene variant implicated in multiple sclerosis (MS) has been determined by researchers at Oxford University. The researchers investigated one particular genetic variant - found in a gene called TNFRSF1A - which has previously been associated with the risk of developing MS.

Featured Genetics Neurology

·July 11, 2012·3 min read

Two Proteins Offer a Clearer Way to Treat Huntington’s Disease

HD mice crossbred with mice that produced greater levels of PGC-1alpha showed dramatic improvement. Production of misfolded proteins was essentially eliminated and the mice behaved normally. “Degeneration of brain cells is prevented. Neurons don’t die,” said La Spada.

Featured Genetics Neurology

·July 9, 2012·4 min read

Researchers Discover Gene Defect for New Syndrome

Research teams discovered a gene defect linked to a cluster of systemic complications, including life-threatening thoracic aortic disease and intracranial aneurysms. The new syndrome is similar, but distinct from known syndromes such as Marfan and Loeys-Dietz syndrome.

Brain Cancer Featured Genetics Neurology

·July 9, 2012·3 min read

Pediatric Tumors Traced to Stem Cells in Developing Brain

Scientists showed in mice that disabling a gene linked to a common pediatric tumor disorder, neurofibromatosis type 1 (NF1), made stem cells from one part of the brain proliferate rapidly. But the same genetic deficit had no effect on stem cells from another brain region.

Featured Genetics Neurology

·July 6, 2012·2 min read

Zebrafish Reveal Promising Mechanism for Healing Spinal Cord Injury

Preliminary results in mice show that Fgf injections near a spinal injury increase both the number of glia cells at the site and the elongated morphology. Their evidence suggests that Fgfs may work to create an environment more supportive of regeneration in mammals as well and could be a valuable therapeutic target.

Genetics

·July 5, 2012·3 min read

Scientists Identify Gene Linked to Facial, Skull and Cognitive Impairment

A gene whose mutation results in malformed faces and skulls as well as mental retardation has been found by scientists.

Featured Genetics Neuroscience

·July 3, 2012·2 min read

Scientists Discover Bees Can “Turn Back Time”, Reverse Brain Aging

Honeybees can reverse brain aging and learning deficits when they take on nest responsibilities usually done by younger bees. Findings suggest social interventions may be used to slow or treat age-related dementia.

Featured Genetics Neuroscience

·July 2, 2012·3 min read

DNA Sequenced for Parrot’s Ability to Parrot

Scientists say they have assembled more completely the string of genetic letters that could control how well parrots learn to imitate their owners and other sounds by using single molecule sequencing.

Autism Featured Genetics Open Neuroscience Articles

·July 2, 2012·3 min read

Researchers Report Success in Treating Autism Spectrum Disorder

Using cyclocreatine, researchers successfully treated an autism spectrum disorder known as creatine transporter deficiency in a mouse model of autism.

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Genetics

Gene Therapy Treatment Extends Lives of Mice with Fatal Disease, Spinal Muscular Atrophy

Neurons Derived from Cord Blood Cells May Represent New Therapeutic Option

Why the Thrill is Gone: Scientists Identify Potential Target for Treating Major Symptom of Depression

Gene Link to Multiple Sclerosis Explains Drug Side Effects

Two Proteins Offer a Clearer Way to Treat Huntington’s Disease

Researchers Discover Gene Defect for New Syndrome

Pediatric Tumors Traced to Stem Cells in Developing Brain

Zebrafish Reveal Promising Mechanism for Healing Spinal Cord Injury

Scientists Identify Gene Linked to Facial, Skull and Cognitive Impairment

Scientists Discover Bees Can “Turn Back Time”, Reverse Brain Aging

DNA Sequenced for Parrot’s Ability to Parrot

Researchers Report Success in Treating Autism Spectrum Disorder

Neuro-Insights of the Week From Neuroscience News, October 1, 2023

Circadian Rhythm Off Beat: Parkinson’s and Nighttime Neuron Damage

ChatGPT’s Role in Shaping Identity and Personal Narratives

New Brain Structures in Language Processing Identified

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