FeaturedNeuroscience·January 18, 2023·3 min readStudy Identifies Cause for Excessive Folding of Gyri in Human Cerebral CortexStudy identifies the role the TMEM161B gene plays in excessive folding of the gyri in the cerebral cortex of those with polymicrogyria.Read More
AutismFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 19, 2023·4 min readExploring the Effect of an Autism-Associated Mutation on Protein MovementsThe autism-associated TOP2B H58Y genetic mutation was significantly less mobile than the TOP2B WT mutation. Researchers say TOP2B H58Y's retrained movement is mediated by ATPase activity.Read More
FeaturedNeurosciencePsychology·January 19, 2023·3 min readPotential Target for Therapeutics Against Eating Disorders IdentifiedUridine, a precursor of RNA, increases hunger when ingested, a new study reports. The findings offer hope for the development of new therapies to help treat those suffering from eating disorders.Read More
FeaturedGeneticsNeurologyNeuroscience·January 20, 2023·4 min readNew Nanoparticles Deliver Therapy Brain-Wide and Edit Alzheimer’s GeneResearchers have developed a new family of nano-scale capsules capable of carrying CRISPR gene editing tools to different organs of the body before harmlessly dissolving. The capsules were able to enter the brains of mice and successfully edit a gene associated with Alzheimer's disease.Read More
FeaturedGeneticsNeurologyNeuroscience·January 20, 2023·5 min readKey Alzheimer’s Risk Factors Affect Men More Than WomenMales with the BIN1 Alzheimer's genetic risk factor and poor vascular health showed steeper and more rapid declines in memory than females.Read More
FeaturedNeurologyNeuroscience·January 20, 2023·6 min readHow Huntington’s Disease Affects Different NeuronsResearchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.Read More
FeaturedGeneticsNeuroscience·January 21, 2023·3 min readNovel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin WrinklesA novel mRNA delivery method that uses extracellular vesicles initiates collagen replacement in photoaged skin. A single injection increased collagen production and reduced wrinkle formation in targeted areas for two months. Researchers say the new delivery method could be used to treat a number of disorders including ones associated with protein loss associated with aging and hereditary disorders where genes and proteins are missing.Read More
Brain CancerFeaturedGeneticsNeuroscience·January 21, 2023·2 min readProtein Movement Reveals Brain Tumor’s Weak SpotIn glioblastoma brain cancer, EGFR (HER1) genetic mutations lead to a movement of a large part of the extracellular region of the protein. This activates the intracellular area in a particular way that drives glioblastoma tumor development.Read More
FeaturedNeuroscience·January 21, 2023·4 min readHow Exercise Might Mitigate Age-Related Decline in Skeletal Muscle Structure and FunctionStudy reveals exercise is associated with myonuclear remodeling and may contribute to the protective effects of exercise on muscle function throughout the lifespan.Read More
FeaturedNeurosciencePsychology·January 21, 2023·5 min readClose Relationships With Parents Promote Healthier Brain Development in High-Risk Teens, Buffering Against Alcohol Use DisorderClose and supportive parental relationships can help mitigate the genetic and environmental risk of developing alcohol use disorder for at-risk teens.Read More
FeaturedGeneticsNeuroscience·January 23, 2023·6 min readAnti-aging Gene Shown to Rewind Heart Age by 10 YearsResearchers say a gene found in many centenarians can reverse the biological age of the heart by ten years. The findings offer a potential target for patients with heart failure.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology·January 24, 2023·3 min readAbnormal 12-Hour Cyclic Gene Activity Found in Schizophrenic BrainsPostmortem brains of those with schizophrenia have fewer genes associated with 12-hour activity cycles in the dorsolateral prefrontal cortex. Mitochondrial-related genes in the dlPFC did maintain a 12-hour rhythm, but their activity did not peak at normal times.Read More
