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Genetics

·October 21, 2012·5 min read

Natural Process Activating Brain’s Immune Cells Could Point Way to Repairing Damaged Brain

The brain’s key “breeder” cells secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding adds a new dimension to our understanding of how resident stem cells and stem cell transplants may improve brain function.

An image of stem cells is shown. Caption describes well.

Featured Neurology

·October 19, 2012·4 min read

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Stem cell study may help to unravel how a genetic mutation leads to Parkinson's symptoms. By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers identified damage to neural stem cells as a powerful player in Parkinson's disease.

Featured Genetics Neuroscience Videos

·October 11, 2012·4 min read

Engineered Flies Spill Secret of Seizures

Scientists have observed the neurological mechanism behind temperature-dependent febrile seizures by genetically engineering fruit flies to harbor a mutation analogous to one that causes epileptic seizures in people. Their new study also highlights the first use of genetic engineering to swap a human genetic disease mutation into a directly analogous gene in a fly.

An image of fly spinal cord equivalent is shown.

Featured Neuroscience

·October 11, 2012·6 min read

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.

Featured Genetics

·October 9, 2012·2 min read

Rare Genetic Disorder Points to Molecules that May Play Role in Schizophrenia

Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia, according to new research. The findings may one day guide researchers to new treatment options for people with schizophrenia - a devastating disease that affects approximately 1 percent of the world's population.

Featured Neurology

·October 3, 2012·3 min read

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating animals with an FDA-approved anesthesia drug, ketamine.

Schizophrenia fMRI brain scans are shown.

Featured Genetics Psychology

·October 3, 2012·4 min read

New de novo Genetic Mutations in Schizophrenia Identified

Columbia University Medical Center (CUMC) researchers have identified dozens of new spontaneous genetic mutations that play a significant role in the development of schizophrenia, adding to the growing list of genetic variants that can contribute to the disease. The schizophrenia study was the largest and most comprehensive of its kind.

Featured Neurology

·October 2, 2012·2 min read

New Research Model to Aid Search for Degenerative Disease Cures

Efforts to treat disorders like Lou Gehrig’s disease, Paget’s disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.

Drawing of a human head with gears and computer parts on it.

Featured Genetics Psychology

·October 2, 2012·2 min read

Intelligence Is in the Genes, but Where?

A new study reveals that most of the specific genes long thought to be linked to intelligence probably have no bearing on one’s IQ. And it may be some time before researchers can identify intelligence’s specific genetic roots.

A patient with Myasthenia Gravis is shown.

Featured Neurology

·October 1, 2012·3 min read

Researchers Halt Autoimmune Disease Myasthenia Gravis in Mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

Featured Neuroscience

·September 21, 2012·4 min read

Research Identifies Protein that Regulates Key Fate Decision in Cortical Progenitor Cells

Researchers solved an important piece of one of neuroscience's outstanding puzzles: how progenitor cells in the developing mammalian brain reproduce themselves while also giving birth to neurons that will populate the emerging cerebral cortex, the seat of cognition and executive function in the mature brain.

Featured Neuroscience

·September 19, 2012·4 min read

Human Brains Share a Consistent Genetic Blueprint and Possess Enormous Biochemical Complexity

Scientists at the Allen Institute for Brain Science reported that human brains share a consistent genetic blueprint and possess enormous biochemical complexity. The findings stem from the first deep and large-scale analysis of the vast data set publicly available in the Allen Human Brain Atlas.

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Genetics

Natural Process Activating Brain’s Immune Cells Could Point Way to Repairing Damaged Brain

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Engineered Flies Spill Secret of Seizures

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

Rare Genetic Disorder Points to Molecules that May Play Role in Schizophrenia

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

New de novo Genetic Mutations in Schizophrenia Identified

New Research Model to Aid Search for Degenerative Disease Cures

Intelligence Is in the Genes, but Where?

Researchers Halt Autoimmune Disease Myasthenia Gravis in Mice

Research Identifies Protein that Regulates Key Fate Decision in Cortical Progenitor Cells

Human Brains Share a Consistent Genetic Blueprint and Possess Enormous Biochemical Complexity

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Circadian Rhythm Off Beat: Parkinson’s and Nighttime Neuron Damage

ChatGPT’s Role in Shaping Identity and Personal Narratives

New Brain Structures in Language Processing Identified

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