Twins who were more physically active had lower signs of metabolic disease and epigenetic markers linked to decreased risk of metabolic syndrome. Findings suggest metabolic diseases are strongly influenced by how a person interacts with their environment as opposed to just their inherited genetics.
CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.
Gene usage in the brains of those who suffered severe COVID-19 infections was similar to that observed in the aging brain. Researchers say COVID-19 is associated with molecular signatures of brain aging.
Low levels of the HDAC4 enzyme caused mice to sleep longer and more deeply than usual.
Aspartame, a sweetener found in diet drinks and food, has been linked to an increased risk of developing anxiety behaviors in a new mouse study. The effects of exposure to aspartame extended for up to two generations.
Areas of the genome associated with brain development harbor variants that seem to account for behavioral differences between dog breeds. The genomic differences between dog breeds are related to the development of their nervous systems. Researchers say genes associated with different dog lineages may relate to genes involved in the development of human behavior.
People with selected variants of the ERAP2 and TICAM2 genes were 40% more likely to survive the Black Death, researchers discovered. However, in modern humans, those with the ERAP2 gene are more likely to suffer autoimmune disorders such as Crohn's disease.
Study identifies genetic markers in cells associated with proprioception. The findings provide new clues about how proprioceptive sensory neurons help control movement.
Researchers have identified a protein that could be leveraged to help microglia in the brain stave off Alzheimer's and other neurodegenerative diseases.
The SLK protein plays a key role in neuron excitability and sensitivity, researchers report.