When T helper cells are absent in the brain, microglia remain suspended between the fetal and adult developmental state. Mice lacking brain T cells showed changes in behavior and defective synaptic pruning. The study reveals the critical role T cells play in the development of the brain.
Researchers have identified a range of psychiatric disorders, including schizophrenia and autism, that share physical characteristics at the molecular level. Specifically, the study identifies common patterns of neural gene expression. In addition, researchers note important differences in gene expression that distinguish the disorders.
Study reveals the role the mouse gene Ophn1 plays in helpless behaviors and identified three methods in which to reverse the effect.
A newly identified gene therapy pathway has the potential to protect us against dementia and cancer, researchers report.
Persistent inflammation may underlie HIV associated neurocognitive disorders in patients taking specific antiretroviral drugs, a new study reports.
Using only enzymes, researchers were able to change synapses between inhibitory and excitatory types.
A new study reveals that most of the specific genes long thought to be linked to intelligence probably have no bearing on one’s IQ. And it may be some time before researchers can identify intelligence’s specific genetic roots.
Research involving programmed cell death has lead to new information about the involvement of a protein named FLIP in cell...
A new study reports teenage binge drinking can result in lasting epigenetic changes that alter the expression of BDNF-AS, a protein vital for the formation of neural connection in the amygdala.
Women who give birth to their last child later in life may have an edge when it comes to longevity. Those who gave birth later in life had longer telomeres, which are biomarkers for long-term health and longevity.
Salk researchers report neurons from people on the autism spectrum exhibit different growth patterns and develop at a faster rate.
UCSF researchers have developed a new genetic risk factor test that takes into account more than 24 genetic variants, each of which are associated with a small risk of Alzheimer's disease. The researchers say the test is a better method to help identify preclinical Alzheimer's than testing for ApoE4 alone.