Researchers have discovered a co-aggregation between amyloid beta and the protein medin in the brains of those with Alzheimer's disease.
Researchers say estimates of how strongly diseases and traits share genetic signals could be over-inflated. Instead, they suggest, mating patterns may help explain the biological relationship between traits.
It is estimated that 80% of autism is inherited, but causative genes are hard to identify. Researchers have identified the ACMSD gene as being associated with non-verbal types of ASD.
A new study will investigate the genetic and biological mysteries of extreme longevity and healthy aging.
Transplanting intestinal epithelial stem cells from healthy donors reduced stroke-induced mortality, decreased the volume of dead brain tissue and gut leakiness, and prevented stroke-induced cognitive decline.
Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.
Children diagnosed with ADHD have a higher genetic overlap with autism spectrum disorder while adults diagnosed with ADHD have a higher genetic overlap with depression.
Results of a phase three clinical trial of a novel brain cancer vaccine, DCVax-L, that uses a patient's stem cells to target cancer cells extend survival by many months to years for glioblastoma patients.
Stress such as intraocular pressure elevation in the eye causes the retinal tissue to undergo transcriptional and epigenetic changes similar to natural aging.
A gene associated with autism overstimulates brain cells far greater in neurons without the mutation.
Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.
A novel compound eliminates disease-causing segments of RNA associated with ALS and dementia, and restores the health of neurons in mouse models.
