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Genetics

·March 31, 2022·12 min read

Now Fully Complete, Human Genome Reveals New Secrets

Newly uncovered complete sequences for formally missing regions of the genome sheds new light on chromosomes and genetic diseases.

This shows neurons and astrocytes in the hippocampus

Electrophysiology Featured Neuroscience

·August 31, 2020·5 min read

Brain Protein Linked to Seizures and Abnormal Social Behaviors

Alterations in the excitation and inhibition balance is regulated in the developing brain by astrocytes via the ephrin-B1 protein. The loss of astrocytic ephrin-B1 alters the E/I balance by reducing inhibition, resulting in hyperactivity of neural circuits. The hyperactivity results in reduced sociability in mice.

Featured Genetics Neurology

·August 14, 2018·3 min read

New Genes that May Contribute to Alzheimer’s Identified

Studying the exomes of 6,000 Alzheimer's patients and 5,000 without the disease, researchers have identified new rare variations in genes that may contribute to dementia.

Autism Featured Genetics

·April 12, 2016·3 min read

Understanding Genes Linked to Autism Relevant Behavior in High Risk Siblings

Researchers report on a link between the dopamine system and initiating joint attention in children at high risk for autism.

Image shows the SMN protein in motor neurons.

Featured Genetics Neurology Open Neuroscience Articles

·April 17, 2017·5 min read

Common Drug Could Help Treat ALS and SMA

Researchers have identified a compound that can stabilize a protein implicated in ALS and SMN.

This image showsn normal cell dividing (left) and stressed cancer cell dividing (right). PLK1 inhibitors stress cancer cells, making them easier to kill.

Brain Cancer Featured Neurology

·May 8, 2015·4 min read

Three Classes of Anti-Cancer Drugs Work in Synergy Against Glioblastoma

Researchers report a combination of three different anti-cancer drugs shows promising results for the treatment of glioblastoma brain cancer.

Featured Genetics Psychology

·July 6, 2016·5 min read

Molecule That Guides Placement of Neurons in Adult Brain May Be Tied to Schizophrenia

According to researchers, miR-19 may be disrupted in cells of some patients with schizophrenia.

Image shows human, mouse and song bird brain maps.

Featured Genetics

·November 15, 2016·5 min read

Genes for Speech May Not Be Limited to Humans

Researchers investigate the effect of a genetic mutation of the FOXP2 gene on the vocalization patterns of adult male mice.

Featured Genetics Neurology Neuroscience

·June 22, 2022·4 min read

ALS May Be Linked to Both the Immune and Central Nervous Systems

Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·March 9, 2020·7 min read

The largest genetic map of psychiatric disorders so far

The largest genetic map of mental health disorders to date reveals there are three groups of highly genetically related disorders among eight psychiatric disorders. A gene related to nervous system development is a risk factor for all eight disorders studied. The RBFOX1 gene is implicated in seven of the eight disorders. ADHD and depression share 44% of genetic risk factors common in the general population. 109 pleiotropic loci affect more than one disorder. These pleiotropic loci are within genes that show heightened expression in the brain through the lifespan, beginning during the second trimester of pregnancy.

Image shows how astrocytes help build neural connections.

Autism Featured Neuroscience

·January 14, 2016·5 min read

Autism Linked Proteins Help Wire the Brain

A new study reveals how three proteins associated with autism and other brain disorders, help to wire up specific areas of the brain responsible for sensory processing.

Featured Genetics Open Neuroscience Articles

·July 26, 2017·4 min read

Genome Editing with CRISPR-Cas9 Prevents Angiogenesis of the Retina

CRISPR gene editing has allowed researchers to prevent angiogenesis of the retina occurring in mice. Researchers say the new technology could help prevent vision loss in those with retinal diseases.

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