The removal of a certain class of potassium channels from the surface of nociceptors is believed to be a key factor in inflammatory pain signaling. Using gene interference to reduce the expression of these specific potassium channels on nociceptors, researchers were able to produce hyperexcitability in nociceptors resembling that seen in inflammatory pain signaling.
After inserting a gene into mice that increases choline transporter and as a result increases acetylcholine at the neuromuscular junctions, the engineered mice were able to run on treadmills twice as long as controls without the inserted gene.
Huntington’s disease research using simple organisms such as baker’s yeast has yielded new information about underlying mechanisms of Huntington’s disease...
New imaging techniques using newly developed stable antibodies and X-ray crystallography allows imaging of the adrenaline receptors for the first...
Max Planck researchers discovered that large, less hydrophobic proteins with a significant increase of disorder in their structures were more...
Neuroscientists found that the specific microRNA, microRNA-29 (miR-29), can make brain cells resistant to programmed cell death. The researchers injected...
The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."
Scientists have discovered genetic mutations in brain tumors that alter brain tumor metabolism. The scientists report that cells with defective...
Parkinson’s disease may be caused by oxidative stress within cells due to defective nucleoli. Dopamine producing neurons are particularly sensitive...
Scientists have shown that stem cells delivered to rats via a nasal spray lead to an improvement of motor functions...
Scientists found that the protein named reelin is deeply involved in the migration of new nerve cells to the neocortex...
Alzheimer’s disease research has lead to important findings involving the tau gene and the possibility of reversing the disease’s progression....
