Gene expression is influence by gamers' degree of social connectedness to others, researchers report. For those with online gaming addiction, the gene expression can lead to chronic stress.
Researchers report just one night of sleep loss can have a tissue specific impact on metabolism and the regulation of gene expression. The study could explain why those who suffer chronic sleep loss or work shifts are at greater risk of obesity and type 2 diabetes.
Researchers report alcohol hijacks a conserved memory pathway in the brain and alters protein expressed in neurons, forming craving that fuel addiction.
Researchers report the CPG2 protein is significantly decreased in the brains of people with bipolar disorder and mutations in the SYNE1 gene undermines the expression of CPG2. The study shows how a set of genetic differences in those with bipolar disorder can lead to specific psychological dysfunction in synapses in the brain. The findings could help improve diagnosis of the disorder and help develop new treatments for BD.
The human development 'clock in a dish' opens up new avenues for research and provides a way to replicate developmental disorders.
Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.
A new study that utilized machine learning tools provides a new map that links genetic signatures to functions across the human brain.
Alterations in long-term social behavior and gene expression were observed in the offspring of mice exposed to pain-killing opioids during pregnancy.
Opioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.
Researchers have created an atlas representing changes in the levels of RNA made in different cell types in the ear following noise-induced hearing loss. They also discovered certain FDA-approved medications for diabetes and other disorders may protect against noise-related hearing loss.
A new post-mortem study identified significant differences in gene expression in two brain areas in patients with bipolar disorder.
Study reveals significant changes in the expression of multiple genes in the placenta associated with exposure to UFP air pollution. Additionally, researchers reported noticeable reductions in fetal and placental length, and fetal weight in those with low dose UFP exposure.
