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gene expression

·August 15, 2021·4 min read

Brain Gene Expression Patterns Altered by Chronic Opioid Use

Opioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.

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·July 26, 2021·3 min read

Administering Opioids to Pregnant Mice Alters Behavior and Gene Expression in Offspring

Alterations in long-term social behavior and gene expression were observed in the offspring of mice exposed to pain-killing opioids during pregnancy.

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·March 25, 2021·3 min read

Study Links Genes With Function Across the Human Brain

A new study that utilized machine learning tools provides a new map that links genetic signatures to functions across the human brain.

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·September 2, 2019·3 min read

Chronic cocaine use modifies gene expression

Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.

This shows cells from the clock in a dish

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·August 29, 2019·4 min read

Human developmental clock mimicked in a dish

The human development 'clock in a dish' opens up new avenues for research and provides a way to replicate developmental disorders.

Featured Genetics Neuroscience Psychology

·January 9, 2019·6 min read

Specific Gene Variants May Raise Bipolar Disorder Risk

Researchers report the CPG2 protein is significantly decreased in the brains of people with bipolar disorder and mutations in the SYNE1 gene undermines the expression of CPG2. The study shows how a set of genetic differences in those with bipolar disorder can lead to specific psychological dysfunction in synapses in the brain. The findings could help improve diagnosis of the disorder and help develop new treatments for BD.

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·October 25, 2018·5 min read

Just a Few Drinks Can Change How Memories Are Formed

Researchers report alcohol hijacks a conserved memory pathway in the brain and alters protein expressed in neurons, forming craving that fuel addiction.

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·August 26, 2018·6 min read

How Sleep May Contribute to Adverse Weight Gain

Researchers report just one night of sleep loss can have a tissue specific impact on metabolism and the regulation of gene expression. The study could explain why those who suffer chronic sleep loss or work shifts are at greater risk of obesity and type 2 diabetes.

Featured Genetics Open Neuroscience Articles Psychology

·June 21, 2018·2 min read

The Psychobiology of Online Gaming

Gene expression is influence by gamers' degree of social connectedness to others, researchers report. For those with online gaming addiction, the gene expression can lead to chronic stress.

Featured Genetics Neuroscience

·April 27, 2018·5 min read

The Written History of a Neuron

Researchers report neurons record their activity in gene expression, and the activity record can be reconstructed by analyzing gene expression patterns.