gene expression

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gene expression

Featured Genetics Neurology Neuroscience

·February 11, 2023·6 min read

Large-Scale Generation of Muscle-Controlling Nerve Cells From ALS Patients

A person's sex is one of the main drivers of altered gene expression in motor neurons, regardless of whether they were derived from patients diagnosed with ALS. Male ALS stem cells generated significantly more motor neurons than the control group, however, this was not seen in female samples.

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Featured Genetics Neuroscience

·August 11, 2022·5 min read

Aging Neutralizes Sex Differences in the Brain

Gene expression in male and female brains becomes more similar due to age, and both sexes contribute to the pattern. If the expression of a gene is higher in younger female brains it tends to be lower in younger male brains. Due to age, the gene expression reduces in females and increases in males, and vice versa.

This shows a drawing of a baby and a placenta

Featured Genetics Neuroscience

·March 11, 2022·4 min read

Air Pollution Can Harm Pregnancy by Affecting Gene Expression in the Placenta

Study reveals significant changes in the expression of multiple genes in the placenta associated with exposure to UFP air pollution. Additionally, researchers reported noticeable reductions in fetal and placental length, and fetal weight in those with low dose UFP exposure.

Featured Genetics Neuroscience Psychology

·March 7, 2022·5 min read

Gene Expression in Brains of People With Bipolar Disorder

A new post-mortem study identified significant differences in gene expression in two brain areas in patients with bipolar disorder.

This is a cartoon of a man speaking loudly and an ear

Auditory Neuroscience Featured Genetics Neuroscience

·October 1, 2021·6 min read

Understanding Hearing Loss From Noise Damage Through Gene Expression Changes

Researchers have created an atlas representing changes in the levels of RNA made in different cell types in the ear following noise-induced hearing loss. They also discovered certain FDA-approved medications for diabetes and other disorders may protect against noise-related hearing loss.

Featured Genetics Neuroscience

·August 15, 2021·4 min read

Brain Gene Expression Patterns Altered by Chronic Opioid Use

Opioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.

Featured Neuroscience

·July 26, 2021·3 min read

Administering Opioids to Pregnant Mice Alters Behavior and Gene Expression in Offspring

Alterations in long-term social behavior and gene expression were observed in the offspring of mice exposed to pain-killing opioids during pregnancy.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 25, 2021·3 min read

Study Links Genes With Function Across the Human Brain

A new study that utilized machine learning tools provides a new map that links genetic signatures to functions across the human brain.

Featured Genetics Neuroscience

·September 2, 2019·3 min read

Chronic cocaine use modifies gene expression

Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.

This shows cells from the clock in a dish

Featured Genetics Neuroscience Neuroscience Videos Open Neuroscience Articles

·August 29, 2019·4 min read

Human developmental clock mimicked in a dish

The human development 'clock in a dish' opens up new avenues for research and provides a way to replicate developmental disorders.

Featured Genetics Neuroscience Psychology

·January 9, 2019·6 min read

Specific Gene Variants May Raise Bipolar Disorder Risk

Researchers report the CPG2 protein is significantly decreased in the brains of people with bipolar disorder and mutations in the SYNE1 gene undermines the expression of CPG2. The study shows how a set of genetic differences in those with bipolar disorder can lead to specific psychological dysfunction in synapses in the brain. The findings could help improve diagnosis of the disorder and help develop new treatments for BD.

Featured Neuroscience

·October 25, 2018·5 min read

Just a Few Drinks Can Change How Memories Are Formed

Researchers report alcohol hijacks a conserved memory pathway in the brain and alters protein expressed in neurons, forming craving that fuel addiction.

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