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GBM

Brain Cancer Featured Neurology Neuroscience

·May 15, 2025·4 min read

Gabapentin Linked to Longer Survival in Glioblastoma Brain Cancer

A new study suggests that gabapentin, a widely used anti-seizure medication, may improve survival in patients with glioblastoma (GBM), the deadliest form of brain cancer. Researchers found that GBM patients taking gabapentin lived several months longer than those who did not, across two independent hospital datasets.

Brain Cancer Featured Genetics Neurology Neuroscience

·May 12, 2025·6 min read

Mapping the Cellular Secrets of Glioblastoma

Two landmark studies have mapped the complex cellular ecosystems of glioblastoma, the deadliest form of brain cancer, offering unprecedented insights into how its diverse cells evolve and resist treatment. Using single-cell RNA sequencing on over 430,000 cells from 59 patients, researchers identified three new glioblastoma cell states and classified tumors into three overarching cellular ecosystems.

Brain Cancer Featured Neurology Neuroscience

·May 9, 2025·3 min read

Glioblastoma Vaccine Trial Moves Forward

The phase 2B SURVIVE trial testing SurVaxM, a cancer vaccine for glioblastoma, will continue as planned following an interim analysis showing sufficient promise to proceed. SurVaxM, combined with standard treatments like surgery, radiation, and chemotherapy, aims to extend survival and improve quality of life for patients with this aggressive brain cancer.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 22, 2025·6 min read

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

A new study reveals that the way DNA folds inside brain cells plays a critical role in glioblastoma, one of the deadliest forms of brain cancer. Researchers discovered that in cancer cells, genes cluster into 3D "hubs" that coordinate tumor-driving activity, even without mutations.

Brain Cancer Featured Neurology Neuroscience

·December 9, 2024·6 min read

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.

Brain Cancer Featured Neurology Neuroscience

·June 6, 2024·6 min read

New Hope for Treating Brain Cancer with Ultrasound

Researchers used ultrasound to penetrate the blood-brain barrier, delivering a chemotherapy and immunotherapy drug combo to treat glioblastoma. This innovative approach boosted the immune system's recognition of cancer cells, showing promise for a new treatment method.

Brain Cancer Featured Neurology Neuroscience

·April 14, 2024·5 min read

Revolutionizing Glioblastoma Treatment

Researchers demonstrated significant initial success using CAR-T therapy for glioblastoma, a notoriously deadly brain cancer. They detailed the outcomes of the first three patients in a Phase 1 clinical trial who experienced dramatic tumor reductions shortly after treatment.

Brain Cancer Featured Neurology Neuroscience

·October 26, 2023·3 min read

Brain’s Fluid Shield May Dim Cancer Treatments: Old Drug Offers Hope

Cerebrospinal fluid, our brain's protective liquid, may be making brain cancers like glioblastoma more resistant to treatments. These findings indicate that when tumor cells are exposed to this fluid, they alter identity, resisting radiation and common medications.

Brain Cancer Featured Neurology Neuroscience

·July 3, 2023·4 min read

Ancient Virus Awakening: Hidden Culprit in Glioblastoma Brain Cancer Aggressiveness

The reactivation of a dormant retrovirus, HML-2, may contribute to the aggressiveness of glioblastoma, a type of brain tumor. Researchers discovered that the virus influences the stem-cell state of the tumors, thereby promoting a more resistant form of cancer.

Brain Cancer Featured Neurology Neuroscience

·February 27, 2023·5 min read

Blood Test for Brain Cancer May Be on Horizon

A new blood-based test to screen for biomarkers of glioblastoma brain cancer has been developed by researchers at Penn State. The test looks for elevated levels of IL13Rα2, an antigen receptor that is derived from glioblastoma tumors.

Brain Cancer Featured Genetics Neuroscience

·January 21, 2023·2 min read

Protein Movement Reveals Brain Tumor’s Weak Spot

In glioblastoma brain cancer, EGFR (HER1) genetic mutations lead to a movement of a large part of the extracellular region of the protein. This activates the intracellular area in a particular way that drives glioblastoma tumor development.

Brain Cancer Featured Neuroscience

·January 16, 2023·3 min read

Using Machine Learning to Predict Brain Tumor Progression

Combining machine learning technology with neuroimaging data, clinicians will be better able to fully analyze a patient's glioblastoma brain tumor and predict cancer progression.

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GBM

Gabapentin Linked to Longer Survival in Glioblastoma Brain Cancer

Mapping the Cellular Secrets of Glioblastoma

Glioblastoma Vaccine Trial Moves Forward

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

New Hope for Treating Brain Cancer with Ultrasound

Revolutionizing Glioblastoma Treatment

Brain’s Fluid Shield May Dim Cancer Treatments: Old Drug Offers Hope

Ancient Virus Awakening: Hidden Culprit in Glioblastoma Brain Cancer Aggressiveness

Blood Test for Brain Cancer May Be on Horizon

Protein Movement Reveals Brain Tumor’s Weak Spot

Using Machine Learning to Predict Brain Tumor Progression

3D-Printed Brain Model Mimics Neural Damage

How the Brain Decides a Smell Is Stinky

Low Sodium Linked to Anxiety Through Brain Chemistry Disruption

How You Take Your Coffee May Impact Your Risk of Early Death

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