Latest

G protein coupled receptors

Image shows researchers looking into a microscope.

Featured Neuroscience

·April 8, 2016·3 min read

A Novel Optogenetic Tool

Researchers use optogenetics to successfully switch specific G-protein coupled signalling pathways on and off.

Illustration of amyloid beta attacking a cell.

Featured Neurology

·October 14, 2015·2 min read

A New Target for Alzheimer’s Disease Treatment

Researchers discovered the GPR3 protein could play an important role in reducing the generation of amyloid beta and in alleviating cognitive deficits in Alzheimer's disease.

This is a sensory neuron in lung tissue.

Featured Neuroscience

·April 16, 2015·5 min read

Sensory Neuron Subtyes Control Different Respiratory Functions

Researchers deconstruct the vagus nerve.

The image shows the mu opioid receptor. The caption best describes the image.

Featured Neuroscience Open Neuroscience Articles

·June 14, 2013·5 min read

Researchers Design Variant of Main Painkiller Receptor

Researchers have developed a variant of the Mu opioid receptor which has several advantages for experimentation The variant can be grown in large quantities and is water soluble, allowing for experiments and applications which have previously been challenging.

The image shows the structure of serotonin. The caption best describes the image.

Featured Neuroscience

·March 21, 2013·7 min read

Study Reveals How Serotonin Receptors Can Shape Drug Effects from LSD to Migraine Medication

Researchers analyze the atomic structure of two types of human serotonin receptors. Their findings could explain why some drugs, which interact with these receptors, occasionally have harmful effects.

The image shows the taste buds of a mouse with specific types of cells highlighted. The caption best describes the image.

Featured Neuroscience

·March 6, 2013·4 min read

How the Body’s Energy Molecule Transmits Three Types of Taste to the Brain

Researchers discovered the CALHM1 channel protein releases ATP to make a neural taste connection.

Electrophysiology Featured Neuroscience

·July 12, 2012·10 min read

Large, Medically Important Class of Proteins Starts to Yield Its Secrets

Five recent research papers shed light on elusive G protein-coupled receptors. New techniques and insights used to solve the GPCR structures are discussed.