Coronaviruses rely on the TOP3B enzyme as a host factor, researchers report. Using artificial intelligence and molecular modeling, researchers were able to identify drug candidates that could serve as TOP3B inhibitors. Studies are now underway to test the drug candidates against living cell cultures and viruses, including COVID-19.
Variations in the TSPO neuroinflammation-associated protein's structure correlates with worse survival outcomes for male glioblastoma brain cancer patients than females.
Researchers report up to 80% of people diagnosed with adult onset ADHD likely do not have the condition. For the 20% of adults who may have ADHD, doctors may have missed the condition during childhood, the researchers conclude.
Study reports medications for ADHD have little detectable impact on how much a child with attention deficit hyperactivity disorder learns in the classroom. However, the medications helped children retain attention, improve classroom behavior, and improve seat-time work.
While learning a second language has positive benefits for children, there is little evidence that bilingual children have more advanced executive function or improved attention over those who are monolingual.