Variations in the TSPO neuroinflammation-associated protein's structure correlates with worse survival outcomes for male glioblastoma brain cancer patients than females.
Coronaviruses rely on the TOP3B enzyme as a host factor, researchers report. Using artificial intelligence and molecular modeling, researchers were able to identify drug candidates that could serve as TOP3B inhibitors. Studies are now underway to test the drug candidates against living cell cultures and viruses, including COVID-19.
While learning a second language has positive benefits for children, there is little evidence that bilingual children have more advanced executive function or improved attention over those who are monolingual.
Researchers report up to 80% of people diagnosed with adult onset ADHD likely do not have the condition. For the 20% of adults who may have ADHD, doctors may have missed the condition during childhood, the researchers conclude.