A new brain tissue study has shown gene expression in bipolar patients treated with antipsychotic medications is similar to the expression in subjects with no history of bipolar disorder.
Researchers report a steroid routinely given to reduce inflammation can alter the expression of a gene associated with fear extinction, preventing the formation of fear memories associated with PTSD.
Early life adversity, coupled with overexpression of the FKBP5 protein, increase susceptibility for later neuropsychiatric disorders, a new mouse study reveals. The association is more pronounced in females.
Study reveals how key proteins regulate the brain's response to stress in the hippocampus.
Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.
Study reports on epigenetic changes to the FKBP5 gene, a key gene associated with the regulation of stress response in the body, in babies and young children who were injured as a result of abuse, but not accidental injury.
