Mice lacking a specific serotonin receptor unlearn fear faster than those with the receptor. The findings open the door to the development of new treatments for PTSD and other disorders associated with fear.
The vulnerability of those with evening chronotypes to anxiety, PTSD, and related disorders may be mediated by altered fear acquisition.
Behavioral inhibition at 12 to 24 months of age was associated with an increased risk of developing depression, more so than anxiety, during later life. This is especially true for inhibited children who showed blunted activity in the ventral striatum during adolescence.
Exposure therapy for fears and phobias may only have a 50% success rate because fear memories outlast competing safety memories learned from therapy. Researchers investigate the genesis of fear memories and have developed a new mathematical model to help strengthen exposure therapies.
Detailed knowledge of probabilities can make dangerous risks seem far less risky, a new study reports.
The TOB gene plays a significant role in reducing depression, anxiety, and fear in mouse models. The findings could have positive implications for developing new treatments for disorders associated with psychiatric stress.
Both those who experienced a natural near-death experience and those who had a near-death experience while taking psychedelics report less fear of death and a lasting, spiritual positive experience.
CGRP neurons found in subregions of the thalamus and brainstem relay multisensory threat information to the amygdala. These neural circuits are essential for the formation of aversive memories, a new study reports.
A child's vaccination or needle fear can be reduced if the nurse spends additional time supporting children during the vaccination process.
Norepinephrine facilitates fear processing by stimulating a population of inhibitory neurons in the amygdala, generating repetitive bursting patterns of electrical activity. This activity changes the frequency of oscillations in the amygdala from resting state to aroused state, promoting the formation of fear memories.