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Erk

·April 27, 2018·5 min read

The Written History of a Neuron

Researchers report neurons record their activity in gene expression, and the activity record can be reconstructed by analyzing gene expression patterns.

Electrophysiology Featured Genetics Neuroscience

·January 27, 2011·3 min read

Myelination, Schwann Cells Devastated in Erk Knock-out Mice

The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."

This shows a tissue sample from the study

Featured Neurology Open Neuroscience Articles

·July 17, 2020·5 min read

Lesion of Doom: How a Parasitic Bacterium Induces Blood Vessel Formation to Cause Lesions

Researchers discovered a bacteria of the genus Bartonella releases a protein, which they dubbed BafA, which stimulates the production of new blood vessels that support bacterial lesions. Bartonella henselae causes cat scratch disease. The findings provide new insight into the mechanisms by which infectious bacteria can produce lesions.

Image shows the chemical structure of acetylcholine.

Featured Neuroscience

·September 18, 2015·4 min read

Coordinating Traffic Down the Neural Highway

Findings could open new avenues for designing drugs to treat ataxia, researchers report.

The image is an MRI showing the location of the amygdala.

Featured Neurology

·September 10, 2013·2 min read

Scientists Discover a Novel Opiate Addiction Switch in the Brain

A new study reveals the underlying molecular process by which opiate addiction develops in the brain.

Featured Genetics Neuroscience Psychology

·February 22, 2019·9 min read

Finding the Elusive Drinking ‘Brake’

Researchers have uncovered a mechanism in the BNST that senses the negative effects of alcohol and modulates the urge to drink. The study reports that when this mechanism doesn't function correctly, we lose the ability to recognize that we have had enough to drink.

Featured Neuroscience Open Neuroscience Articles

·September 29, 2022·4 min read

Unraveling the Reward Behavior: The Mechanisms Underlying the Dopamine Signaling Pathway

The direct phosphorylation of KCNQ2 by ERK occurs through the activation of the dopamine signaling pathway in the nucleus accumbens of mice.

This shows three computerized heads against a swirly background

Featured Neuroscience Psychology

·September 30, 2019·3 min read

Cannabis study reveals how CBD offsets the psychiatric side-effects of THC

CBD blocks the ability of THC to overstimulate the ERK pathway in the hippocampus, preventing negative side effects associated with cannabis use.

Featured Genetics

·September 13, 2018·4 min read

Disrupting Genetic Processes Reverses Aging in Human Cells

Researchers report certain genes and pathways that regulate slicing factors play a critical role in the aging process. Disrupting these genetic processes, researchers say, could reverse signs of aging in human cells.

Featured Neurology

·July 20, 2020·4 min read

Oxytocin Could Be Used to Treat Cognitive Disorders Like Alzheimer’s

Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.