Common epigenetic markers associated with food addiction have been identified.
Researchers used epigenetic modulators to reduce the damage done by stress to neuroplasticity. Findings reveal acute intervention in epigenetic mechanisms produced antidepressant effects more rapidly than conventional medications.
Marijuana use alters a gene associated with autism in sperm. Hypomethylation was identified in the DLGAP2 gene in the sperm of male rats exposed to THC. The hypomethylated state was also detected in the forebrains of their offspring. Further research is needed to establish if there is a definitive link between paternal cannabis use and ASD in humans.
In mice, the failed epigenetic suppression of Xist leads to fetal developmental abnormalities and miscarriage. Knocking out the Xist gene greatly reduced prenatal death. The findings have implications for understanding infertility and developing new treatments to prevent miscarriage.
A pre-clinical mouse study may provide an exciting new step toward developing new treatment approaches for Fragile X.
Researchers have released data from the world's largest brain and body scanning study.