Cannabinoid receptors have been identified in the central nucleus of the amygdala, a key emotional hub in the brain.
A new study reports on how endocannabinoids are affected by sleep deprivation and whether exercise can modulate the effect.
For people with arthritis, exercise reduces pain and lowers levels of inflammatory cytokines. Exercise also increases the production of natural endocannabinoids. Researchers found the way exercise promotes these changes was due to altered gut microbes.
An imbalance in gut bacteria can cause the reduction of some metabolites, resulting in depression-like symptoms. The findings contribute to the growing body of evidence for the role the microbiome plays in brain function and mental health.
A new study suggests developing new therapeutics that use cannabinoid receptors to treat chronic pain.
When pregnant women consume diets high in polyunsaturated omega-6 fatty acids, an excess of endocannabinoids is produced which overloads the fetus, and impairs healthy brain development.
Researchers have created the most detailed 3D structure to date of the brain receptor that binds and responds to the root of the marijuana high.
The release of 2-AG, a natural endocannabinoid that is suggested to be the brain's equivalent to THC, dampens down seizure activity but increases post-seizure oxygen deprivation in the brain.
According to researchers, cannabinoids can reduce cravings and help ease withdrawal for those addicted to opioids.
Researchers report deficiencies of natural cannabinoids could result in a predisposition for developing depression and PTSD. Boosting the system could help in treating stress related disorders.