Dopamine D2 receptor overexpression in cholinergic interneurons of the nucleus accumbens may explain why some are more prone to cocaine addiction than others.
Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.
A new study reveals the combination of ketamine with naltrexone can help treat symptoms of both depression and addiction.
A new study looks at the epigenetic factors that contribute to drug addiction and influence relapse.
Researchers outline how cravings may occur in the brain.
Findings suggest brain networks associated with impulse control could be weakened in people with gambling addiction.
According to researchers, non-medical use of prescription opioids has more than doubled among US adults within a 10 year period.